14105-1-AP targets ARNT/HIF-1 beta in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

2021年6月21日 · SET1B loss leads to a selective reduction in transcriptional activation of HIF target genes, resulting in impaired cell growth, angiogenesis and tumor establishment in SET1B-deficient xenografts....

The HIF1 beta subunits (HIF1B), also known as aryl hydrocarbon receptor nuclear translocators (ARNT), are encoded by two genes ARNT1 and ARNT2. HIF1B is stably expressed and is also an obligate partner for the aryl hydrocarbon receptor (AHR) (Hoffman et al., 1991, Wang et al., 1995, McIntosh et al., 2010).

Here, we demonstrate that SF3B1 is a hypoxia-inducible factor (HIF)-1 target gene that positively regulates HIF1 pathway activity. By physically interacting with HIF1α, SF3B1 facilitates binding of the HIF1 complex to hypoxia response elements (HREs) to activate target gene expression.

2020年3月3日 · Hypoxia-inducible factor 1 (HIF1) is a heterodimeric transcription factor, consisting of a constitutively expressed β-subunit (HIF1B) and a regulated α-subunit (HIF1A). In...

14105-1-AP targets ARNT/HIF-1 beta in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

GeneTex验证 HIF1 beta抗体 (GTX30109).可与 Human, Mouse, Rat, Sheep, Bovine, Ferret 样本反应。可应用于 WB, ICC/IF, IHC-P, IP, ChIP assay, Gel supershift assays。

HIF-1β/ARNT Antibody detects endogenous levels of total HIF-1β/ARNT protein. Human, Mouse, Rat, Monkey. Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to the sequence of human HIF-1β/ARNT. Antibodies are purified by protein A and peptide affinity chromatography.