Called hikeshi-banten, a Japanese fireman's jacket was a handmade garment made up of several layers of highly absorbent indigo cotton fabric. The firemen drenched their jackets with water before beginning to fight the fire.

2024年12月25日 · HIKESHI (Heat Shock Protein Nuclear Import Factor Hikeshi) is a Protein Coding gene. Diseases associated with HIKESHI include Leukodystrophy, Hypomyelinating, 13 and C11orf73-Related Autosomal Recessive Hypomyelinating Leukodystrophy .

2015年9月3日 · From the rambunctious hikeshi, to the libertine otokodate, to the modern yazkuza, this series weighs reality against the prevailing myths of these unconventional heroes. Built of wood, bamboo, straw and paper, the city of Edo lived in constant fear of fire.

2023年11月6日 · Mutation in Hikeshi, encoding a nonconventional nuclear import carrier of heat shock protein 70 family (HSP70s), leads to inherited leukodystrophy; however, the pathological mechanisms remain elusive. Here, we showed that Hikeshi is essential for central nervous system (CNS) myelination.

The protein encoded by HIKESHI, Hikeshi, mediates the heat stress-induced nuclear import of heat shock protein (Hsp70) through a nuclear pore complex. 8,9 Upon nuclear translocation, HSP70 dissociates from Hikeshi and exerts its protective functions as a molecular chaperone.

2012年4月27日 · Here, we identify a nuclear import pathway that operates during heat shock stress and is mediated by an evolutionarily conserved protein named "Hikeshi," which does not belong to the importin β family.

2025年2月8日 · identify a nuclear import pathway that operates during heat shock stress and is mediated by an evolutionarily conserved protein, Hikeshi (coded by the C11orf73 gene) binds to FG-Nups and translocates through nuclear pores on its own, showing characteristic features of nuclear transport carriers.

In the early 19th century, firemen in Japan were commonly known as “hikeshi”, and their primary duty was to combat fires. They were often recruited from the lower classes and organized into teams, known as “machi-bikeshi”, which were responsible for …

Hikeshi (Japanese: 火消 [a]) were fire brigades in Edo and Meiji-era Tokyo; also members of these brigades. Utagawa Yoshitora, Hikeshi with a matoi. Japanese cities were extremely prone to fires due to the fact that paper and wood were the main building materials.

2004年4月21日 · Hikeshi - Born to be Wild. By 1738, Edo employed over 11,000 firefighters for a population of around one million. This number grew to 24,000 hikeshi by 1850. Their main task was to contain fires by demolishing nearby structures.