CHO （Chinese hamster ovary cell）是源自 中国仓鼠 卵巢 的 上皮 细胞系，通常应用于 生物学 和 医学 研究，并且在商业上用于生产具治疗性的 蛋白质 [1]。 它们已广泛用于 遗传学 、毒性筛选，以及 营养 方面和 基因表达 的研究，特别是表达重组蛋白。 CHO细胞同时是用于重组蛋白治疗剂工业生产的最常用的 哺乳动物 宿主 [1]。 中国仓鼠自1919年以来就被广泛用于多项研究，可以代替 小鼠 来引 肺炎链球菌 入其 体内。 随后发现它们是传播 内脏性利什曼病 （英语：Visceral …

2024年11月9日 · Chinese hamster ovary (CHO) cells are the backbone of modern biopharmaceutical manufacturing, especially in the production of monoclonal antibodies (mAbs) and other therapeutic proteins.

CHO细胞(Chinese Hamster Ovary cells，中国仓鼠卵巢细胞)是一种来源于中国仓鼠卵巢细胞的实验室培养细胞系。 中国仓鼠于1948年被带到美国，1957年，T.Puck从波士顿癌症研究基金会的实验室获得了一只中国仓鼠，在那…

Chinese hamster ovary (CHO) cells dominate biotherapeutic protein production and are widely used in mammalian cell line engineering research. To elucidate metabolic bottlenecks in protein production and to guide cell engineering and bioprocess ...

2023年6月30日 · CHO Cloning MaxA克隆培养基是迈邦利用CHO细胞代谢途径开发的一款适合单细胞 悬浮 生长的化学成分明确的培养基，适用于 CHO-K1、 CHO-K1SV 、CHOZN 等多种CHO细胞系单细胞悬浮培养。

2019年9月10日 · Host cell proteins (HCPs) are process-related impurities derived from the host organism such as Chinese hamster ovary (CHO) cells used for the production of therapeutic mAbs in biopharmaceuticals and potentially pose a risk to patient safety and product efficacy.

Cho Kiho, Lee Hak Joo, Kim Jae Hyun, Kim Jong Man, Kim Yong Kweon, Baek Chang Wook. A study of nano-indentation test using rhombus-shaped cantilever in atomic force microscope, Key Engineering Materials 2006; 326-328: 207-210 doi:10.4028/www.scientific.net/KEM.326-328.207

KH Cho, PGM Mileo, JS Lee, UH Lee, J Park, SJ Cho, SK Chitale, ... ACS Applied Materials & Interfaces 13 (1), 1723-1734, 2021. 36: 2021: Amine and fluorine co-functionalized MIL-101 (Cr) synthesized via a mixed-ligand strategy for CO2 capture under humid conditions.

2024年10月1日 · We create algorithmic solutions to tackle a variety of computational challenges introduced by the large-scale, heterogeneous, and private aspects of genomic and health-related data. How can we share and analyze sensitive data with privacy, and better understand the risks of modern data sharing practices?

CHO-K1 or Chinese hamster ovary cell line K1 is a subclone of parental CHO cells that originated from the biopsy of an adult female Chinese hamster ovary in 1957. The original cell line was developed by T.T. Puck and colleagues at the University of …