
Hla Hla Yi - Facebook
Hla Hla Yi is on Facebook. Join Facebook to connect with Hla Hla Yi and others you may know. Facebook gives people the power to share and makes the world more open and connected.
Distributions of HLA-A and -B alleles and haplotypes in the Yi …
Objective: To investigate the distributions of human leukocyte antigen (HLA)-A and -B alleles and HLA-A-B haplotypes in the Yi ethnic minority of the Yunnan Province, situated in southwestern China. Methods: DNA typing for HLA-A and -B loci was performed using the polymerase chain reaction-sequence-based typing (PCR-SBT) method on 114 randomly ...
免疫系统之 HLA 与MHC - 知乎 - 知乎专栏
HLA -II型 (HLA-DP, HLA-DM, HLA-DO, HLA-DQ, HLA-DR)编码第二型MHC,将细胞外抗原呈递给CD 4+ T(T-helper cells 辅助T细胞),T细胞增殖,进而刺激B细胞产生抗原特异性抗体(体液免疫)。
【绘真科普】人类白细胞抗原(HLA)如何指导肿瘤免疫治疗疗 …
hla loh会造成hla的表达降低,但hla基因型改变对此影响不大,hla loh相比基因型变化,更能影响免疫逃逸机制以及免疫药物的疗效。 因此,相对而言,肿瘤患者检测HLA LOH比HLA基因型对免疫指导意义更高。
免疫检查点抑制剂生物标志物之HLA - 知乎 - 知乎专栏
hla-ii类基因包括hla-d家族,主要有hla-dp、hla-dq和hla-dr等,主要分布于b淋巴细胞、巨噬细胞和树突状细胞等专职抗原提呈细胞表面。hla-iii类基因大约包含75个基因,大多数功能不明。
(PDF) Distributions of HLA-A and -B alleles and haplotypes in the Yi ...
2010年2月1日 · DNA typing for HLA-A and -B loci was performed using the polymerase chain reaction-sequence-based typing (PCR-SBT) method on 114 randomly selected healthy individuals of the Yi population.
人HLA(MHC)分型类别及分型方法介绍 - 儒百生物科技
2019年5月4日 · HLA分型即是检出HLA多态性,主要有两大类检出方法,分别是检出HLA编码分子的抗原特异性(血清学和细胞学分型)或检出各等位基因的DNA序列(基因分型)。 两类检出方法对应两种HLA命名方法。 血清学和细胞学分型技术建立于上世纪60年代,从70年代到80年代末期主要是血清学研究,侧重于分析HLA产物特异性。 1991年第11届国际HLA专题讨论上提出HLA的DNA分型方法,随着测序技术的突飞猛进,基于DNA序列的分型方法正在逐步取代传统的血 …
[Genotyping of HLA-Cw locus in Chinese Yi ethnic group by PCR …
This study provides the data of HLA-Cw gene frequency in Chinese Yi ethnic group, which may contribute to research on anthropology, disease association and vaccine application. The result also confirmed that PCR-SSP was a reliable and fast method for HLA-Cw genotyping.
Investigations of sequencing data and sample type on HLA …
2020年7月14日 · In this study, we conducted performance evaluations of 4 widely used HLA typing tools (OptiType, Phlat, Polysolver and seq2hla) for predicting HLA class Ia genes from WES and RNA-seq data of 28 cancer patients.
何谓人类白细胞抗原(HLA)及主要组织相容性抗原(MHC)
人类的MHC称为HLA,即人类白细胞抗原(human leukocyte antigen, HLA)。 HLA是由HLA基因复合体所编码的产物。 HLA作为基因研究时,代表一组密切连锁的基因群,称为HLA基因复合体,简称HLA复合体;若作为抗原研究时,则指由这群基因复合体所编码的抗原称为HLA系统 ...
- 某些结果已被删除