HLA-B13 (B13) is an HLA-B serotype. The serotype identifies the more common HLA-B*13 gene products. [1] (For terminology help see: HLA-serotype tutorial)

An association with HLA-B13 was first identified and later with other class I antigens HLA-B17, -B37, -B57, -Cw6 and Cw7, and class II antigens HLA-DR4 and -DR7. Among these, the …

HLA-B13 is a genetic locus that has been implicated in the predisposition to Psoriasis (Ps) and Psoriatic Arthritis (PsA), showing a strong association with these conditions within the major …

2013年10月24日 · HLA-B*13:01 is present in about 2 to 20% of Chinese persons, 1.5% of Japanese persons, 1 to 12% of Indians, and 2 to 4% of Southeast Asians but is largely absent …

研究确定的氨苯砜综合征风险位点hla-b*1301，其敏感度和特异度分别达86.8%、85.7%。 研究人员表示，风险位点HLA-B*1301发现后，可通过用药前检测，来有效预防氨苯砜综合征的发生。

2022年8月13日 · Results showed the crystal structure of HLA-B*13:01-beta-2-microglobulin (β2M) complex at 1.5 Å resolution and performed mutation assays demonstrating that I118 or I119, …

2021年5月4日 · HLA-B*13:01 allele has been identified as the genetic determinant of dapsone hypersensitivity syndrome (DHS) among leprosy and non-leprosy patients in several studies. …

人类白细胞抗原（human leukocyte antigen, HLA）是由HLA基因复合体所编码的产物，定位于第6染色体短臂上。 HLA系人类组织相容性复合体（MHC）的表达产物，是构成移植排斥反应的 …

2020年10月16日 · The results of HLA-typing showed that HLA-B*13:01 was the most significant allele associated with DHS, with odds ratio = 233.64 and P-value = 7.11×10-9, confirming the …

2023年8月4日 · HLA-B*13:01基因检测用于计划服用氨苯砜治疗麻风病等疾病患者的用药指导,以避免氨苯砜 综合征 不良反应。 氨苯砜综合征 (DHS)是氨苯砜治疗后出现的严重不良反应,属于药 …