HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1; [1] later, it was among 3 types DQw1 (later …

HLA-DQ (DQ) is a cell surface receptor protein found on antigen-presenting cells. It is an αβ heterodimer of type MHC class II. The α and β chains are encoded by two loci, HLA-DQA1 …

HLA typing allows to define a CD risk gradient associated with each particular HLA-DQ status (DQA1 and DQB1 alleles and their combinations) and DQB1*02 homozygosity/heterozygosity …

2012年10月11日 · Celiac disease is a common multifactorial disorder in which specific HLA-DQA1 and HLA-DQB1 alleles represent the major genetic predisposition. HLA typing, however, does …

The HLA-DQA1 gene provides instructions for making a protein that plays a critical role in the immune system. The HLA-DQA1 gene is part of a family of genes called the human leukocyte …

HLA-DQ1 is a specific genetic marker that is often found in confirmed narcoleptic patients, including those with narcolepsy/cataplexy. It is one of the markers associated with narcolepsy, …

HLA-DQA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the …

A strong association between narcolepsy and specific class II HLA antigens (DR2 and DQ1, 100% vs 30%) was first noted in the Japanese population. 1 HLA class II antigens are present on …

At the population level the strongest genetic association with T1D is with HLA-DQ alleles. This is best defined by DNA typing of HLA-DQ1, DQB1, and DRB1. However, due to the strong …

HLA-DQ1 is a serotype that covers a broad range of HLA-DQ haplotypes. Historically it was identified as a DR-like alpha chain called DC1, later, it was among 3 types DQw1 (later DQ1, …