HLA-DQ6 (DQ6) is a human leukocyte antigen serotype within HLA-DQ (DQ) serotype group. The serotype is determined by the antibody recognition of β 6 subset of DQ β-chains. The β-chain …

HLA-DQ (DQ) is a cell surface receptor protein found on antigen-presenting cells. It is an αβ heterodimer of type MHC class II. The α and β chains are encoded by two loci, HLA-DQA1 …

HLA-DQ6 refers to a specific allele found more frequently in patients of African ancestry with scleroderma, showing a higher frequency in individuals with AFA. You might find these …

HLA B7-DR15-DQ6 is a multigene haplotype that covers a majority of the human major histocompatibility complex on chromosome 6. A multigene haplotype is set of inherited alleles …

2022年8月30日 · Svaret gis ut som HLA-DQ6 positiv (hvis vi påviser HLA-DQB1*06:02) eller negativ. HLA-typing kan ikke brukes for å påvise sykdom. De fleste narkolepsi-pasienter er …

2023年8月21日 · To verify the gene expression of the beta chain of HLA-DQ6, we determined HLA-DQB1 mRNA expression using Q-RT-PCR in the nonmanipulated controls (BLS-1), in JY …

2008年6月1日 · Human population studies have suggested that HLA-DQ6 (DQB1*0601) may be a protective gene in MS. To test this disease protection in an experimental model, we generated …

HLA-DQ6 is an HLA-DQ serotype grouping based on antibody recognition of the HLA DQ beta chain. It is synonymous with the HLA-DQB1*06 allelegroup. This group is composed of many …

DR15-DQ6 was associated with decreased risk of diabetes relative to a neutral HLA genotype throughout the first five decades of life in UK Biobank (Fig. 2). This protection was dominant as …

2000年2月1日 · The mechanisms by which HLA-DQ6 molecules control the development of diabetes and protect auto immune reactions to specific β cell antigens are not understood. …