Major histocompatibility complex, class II, DR beta 4, also known as HLA-DRB4, is a human gene. [2] The protein encoded by this gene belongs to the HLA class II beta chain paralogues. …

2024年12月25日 · HLA-DRB4 (Major Histocompatibility Complex, Class II, DR Beta 4) is a Protein Coding gene. Diseases associated with HLA-DRB4 include Hla Modifier and Lymphoma. …

HLA-DR4 is a susceptibility factor for the development of AIH. Impaired suppressive function of Tregs and reduced PD-1 expression may result in spontaneous activation of key immune cell …

2024年1月3日 · Our study is the first to suggest that patients with metastatic NSCLC patients on ICI therapy with HLA-DRB4 genotype experience improved survival outcomes. Patients with …

Super high-resolution single molecule sequence-based typing (SS-SBT) is a human leukocyte antigen (HLA) DNA typing method to the field 4 level of allelic resolution (formerly known as …

2023年12月27日 · Gene target information for HLA-DRB4 - major histocompatibility complex, class II, DR beta 4 (human). Find diseases associated with this biological target and …

Human leukocyte antigen (HLA) is emerging as a possible predictive biomarker. Our study aimed to assess HLA class II genotypes and their correlation to irAEs and survival.

2024年6月6日 · Summary HLA-DRB4 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both …

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DRB4*01:01 (DRB4) is a secondary HLA-DR product which is part of the high risk DR4/DQ8 haplotype that is associated with type 1 diabetes (T1D). DRB4 shares considerable homology …