Heme oxygenase-1 (HO-1), a stress protein and metabolic enzyme, continues to attract worldwide basic and translational research interest as a regulator of cellular and tissue homeostatic …

Heme-oxygenase 1 (HO-1) is a microsomal enzyme released by cell stressor triggers and may play a role as an anti-inflammatory molecule.

One such stress-response protein is heme oxygenase-1, HO-1. Since the identification of HO-1 in 1968, many of the studies involving this enzyme were understandably focused on the …

2021年1月29日 · This Review provides an overview of haem oxygenase 1 (HO-1) for immunologists, including its roles in iron metabolism and antioxidant defence, and the impact …

2009年9月1日 · Heme oxygenase (HO)-1 is an inducible enzyme that catalyzes the first and rate-limiting step in the oxidative degradation of free heme into ferrous iron, carbon monoxide (CO), …

Heme oxygenase-1 (HO-1) catalyzes the degradation of heme with consequent production of free iron, carbon monoxide, and the linear tetrapyrrole biliverdin. The latter is converted to bilirubin …

2021年9月13日 · Heme oxygenases (HOs) act on heme degradation to produce carbon monoxide (CO), free iron, ferritin, and biliverdin. Upregulation of cellular HO-1 levels is signature of …

HO is a family of ubiquitously expressed enzymes which regulate the regiospecific catabolism of heme leading to the formation of equimolar amounts of carbon monoxide (CO), ferrous iron …

2012年7月18日 · Heme oxygenase-1 (HO-1) is a Nrf2-regulated gene that plays a critical role in the prevention of vascular inflammation. It is the inducible isoform of HO, responsible for the …

2015年3月21日 · Heme oxygenase-1 (HO-1) is a rate-limiting enzyme catalyzing oxidative degradation of cellular heme to liberate free iron, carbon monoxide (CO) and biliverdin in …