2014年9月16日 · The protein kinase Hog1 (high osmolarity glycerol 1) was discovered 20 years ago, being revealed as a central signaling mediator during osmoregulation in the budding …

The protein kinase Hog1 (high osmolarity glycerol 1) was discovered 20 years ago, being revealed as a central signaling mediator during osmoregulation in the budding yeast …

2006年10月18日 · Hog1p is a mitogen-activated protein kinase (MAPK) integral to the osmoregulatory signal transduction cascade (HOG signaling pathway) which affects gene …

Hog1是第一个被发现能传递渗透胁迫信号的MAPK，也是在真菌中最具特征的MAPKs之一。 它是核心级联反应的关键MAPK，控制菌株的转录、翻译、运输和细胞周期适应胁迫 [75]。

The high-osmolarity glycerol (HOG) signalling pathway, comprising Ste11/Ssk2/Ssk22 (MAPKKK), Pbs2 (MAPKK), and Hog1 (MAPK), is an important and conserved pathway in fungi. However, …

In Saccharomyces cerevisiae, osmostress induces the high-osmolarity glycerol (HOG) pathway, which includes Hog1. Upon activation in response to osmostress by upstream sensors and …

In response to hyperosmotic environments, most eukaryotic cells activate a specialized mitogen-activated protein (MAP) kinase pathway. In S. cerevisiae, the key protein kinase, Hog1, …

丝裂原活化蛋白激酶 (MAPK)信号通路广泛存在于真核细胞并且高度保守,是生物体内非常重要的信号转导系统之一.胞外刺激信号通过细胞膜上的特异性受体传递给胞内MAPK信号通路,该信号 …

Here, we highlight the mechanism by which cells sense changes in extracellular osmolarity, the method by which Hog1 regulates cellular adaptation, and the im-pacts of the Hog1 pathway …

2022年3月25日 · Hog1 is a member of the family of p38 SAPKs, which are present across eukaryotes. Many of the properties of the HOG pathway and downstream-regulated proteins …