2024年12月25日 · HOXA2 (Homeobox A2) is a Protein Coding gene. Diseases associated with HOXA2 include Microtia, Hearing Impairment, And Cleft Palate and Bilateral Microtia …

HOXA2 controls the embryonic development of the lower and middle part of the face and of the middle ear. Mutations in it are known to cause microtia, hearing impairment, and cleft palate.

HOXA2 acts as a suppressor or TBP-antagonist to inhibit MMP-9 expression; while methylation-mediated inactivation of HOXA2 in NPC derepresses MMP-9 production and increases …

Results showed that HOXA2 is highly expressed in tumor tissues compared to normal tissues. Overexpression of HOXA2 contributes to the activation of the JAK-STAT signaling pathway, …

2025年1月20日 · Low HOXA2 expression correlated with increased BC aggressiveness and unfavorable patient survival outcomes. Suppression of HOXA2 expression significantly …

2009年1月20日 · Here we present a comprehensive analysis of HOX expression in non-small-cell lung cancer (NSCLC) that reveals that many of the HOX genes have strongly elevated …

Hox在传递本体感觉的脊髓小脑束神经元(spino cerebellar tract neuron, SCTN) 的发育中起重要作用, Hox功能的丧失导致SCTN 亚型特殊转录程序的异常, 导致本体感觉神经元、SCTNS 和小 …

Hoxa2 belongs to the mammalian Hox genes family that encodes 39 highly conserved homeodomain transcription factors mainly involved in embryonic development but also in a …

We observed that the levels of HOXA2, HOXA9, and HOXA10 were associated with the levels of immune infiltration of several kinds of immune cells. Overall, our findings identified the …

HOXA2 has been shown to be critical for outer and middle ear development through mouse models and has previously been associated with autosomal recessive bilateral microtia. Our …