2023年4月3日 · HRS-AKI is due to intense renal vasoconstriction, causing renal hypoperfusion. As such, it may be conceptualized as a reversible form of “pre-renal” renal failure. If hemodynamic abnormalities are reversed, HRS-AKI is expected to resolve.

2020年9月14日 · The first represents an acute impairment of kidney function, HRS-AKI, whereas the second represents a more chronic kidney dysfunction, HRS-CKD (chronic kidney disease). In this review, we provide critical insight into the definition, pathophysiology, diagnosis, and management of hepatorenal syndrome.

2023年8月8日 · Hepatorenal syndrome (HRS) is a multiorgan condition of acute kidney injury seen in those with advanced liver disease. Patients with this condition present with signs and symptoms of liver failure as well as decreased urination as they become oliguric.

What is hepatorenal syndrome (HRS)? Hepatorenal syndrome (HRS) is a life-threatening complication of advanced liver disease that affects your kidney function. It causes prerenal acute kidney failure. That means that it comes on suddenly, without any previous kidney disease or any physical changes to the kidneys themselves. Your kidneys may be ...

HRS is the extreme form of kidney injury in patients with cirrhosis, which is caused due to a reduction in renal blood flow unresponsive to volume expansion. The literature involving HRS is rapidly evolving and newer tests and updated definitions have been proposed which allows timely identification and treatment.

Acute kidney injury (AKI) in cirrhosis, including hepatorenal syndrome (HRS), is a common and serious complication in cirrhotic patients, leading to significant morbidity and mortality. AKI is separated into two categories, non-HRS AKI and HRS-AKI.

2024年3月23日 · Patients with HRS-AKD meeting AKI criteria are classified as having HRS-AKI. HRS for less than 90 days would be classified as HRS-AKD, while HRS persisting for more than 90 days would be classified as HRS-CKD. In contrast, a patient with pre-existing CKD (e.g., diabetic nephropathy) who develops HRS-AKI would be classified as having HRS-AKI on ...

2023年2月22日 · Definitions of Acute Kidney Injury (AKI) and the Hepatorenal Syndrome (HRS) in Patients with Cirrhosis. In general, the three main causes of AKI 11 are renal hypoperfusion (also referred to as...

2022年6月5日 · HRS-NAKI包括了肝肾综合征-急性肝病（HRS-AKD）和肝肾综合征-慢性肝病（HRS-CKD）。 HRS-AKD指：（1）除了HRS-AKI以外，肝硬化伴或不伴腹水；（2）3个月内肾小球滤过率（eGFR）＜60 ml·min^-1·1.73 m^-2，没有其他器质性病变；或（3）3个月内Scr的最后可用值作为基线值，Scr＜50％的百分比增加。 与HRS-AKD不同，HRS-CKD的诊断需要eGFR＜60 ml·min^-1·1.73 m^-2超过3个月。 与HRS-AKI相比，HRS-NAKI患者的器官功能衰竭 …

Hepatorenal syndrome (HRS) is a serious complication of end-stage cirrhosis and portal hypertension that is characterized by increased splanchnic blood flow, a state of decreased central volume, kidney blood flow and glomerular filtration rate (GFR) [1].