2024年12月25日 · HSD17B8 (Hydroxysteroid 17-Beta Dehydrogenase 8) is a Protein Coding gene. Diseases associated with HSD17B8 include Dystonia, Childhood-Onset, With Optic Atrophy And Basal Ganglia Abnormalities and Israeli Tick Typhus. Among its related pathways are Estrone metabolism and Metabolism.

Estradiol 17 beta-dehydrogenase 8 is an enzyme that in humans is encoded by the HSD17B8 gene. [5] [6] [7] In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens.

2024年5月29日 · F12E12.11 is an ortholog of human estradiol 17-beta-dehydrogenase 8 (HSD17B8), which converts estradiol to estrone through its NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. We...

在小鼠中，Ke6 蛋白是一种 17-β-羟基类固醇脱氢酶，可以调节具有生物活性的雌激素和雄激素的浓度。 它优先是一种氧化酶并使雌二醇、睾酮和二氢睾酮失活。 然而，该酶具有一定的还原活性，可以从雌酮合成雌二醇。 该基因编码的蛋白质与 Ke6 相似，是短链脱氢酶超家族的成员。 已检测到该基因的可变剪接转录本，但尚未确定该变体的全长性质。 [RefSeq 提供，2008 年 7 月] In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the …

Hs17beta-HSD8 and HsCBR4 show a strong genetic interaction in vivo in yeast, where, only if they are expressed together, they rescue the respiratory deficiency and restore the lipoic acid content of oar1Delta cells.

The Obesity-Related Metabolic Gene HSD17B8 Protects Against Breast Cancer: High RNA/Protein Expression Means a Better Prognosis. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic.

HSD17B8 is a prognostic marker in Kidney renal clear cell carcinoma, Kidney renal papillary cell carcinoma, Liver hepatocellular carcinoma

2016年9月14日 · Gene target information for HSD17B8 - hydroxysteroid 17-beta dehydrogenase 8 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

hsd17b8的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为在小鼠中，ke6蛋白质是17-β-羟基类固醇脱氢酶，可以调节生物活性的雌激素和雄激素的浓度。

Enables estradiol 17-beta-dehydrogenase activity and testosterone dehydrogenase (NAD+) activity. Acts upstream of or within androgen metabolic process and estrogen metabolic process. Located in mitochondrial envelope and plasma membrane.