2023年4月30日 · An abnormal Pap smear result of high-grade squamous intraepithelial lesion (HSIL) means that an area of cells of the cervix (the narrow neck of the uterus) looks abnormal when examined under a microscope.

2023年11月12日 · High-grade squamous intraepithelial lesion (HSIL) is a squamous cell abnormality associated with human papillomavirus (HPV). It encompasses the previously used terms cervical intraepithelial neoplasia grades 2 and 3 (CIN 2 and CIN 3), moderate and severe dysplasia, and carcinoma in situ.

2024年6月6日 · CIN is graded on a scale of 1 to 3, based on how abnormal the cells look under a microscope and how much of the cervical tissue is affected. LSIL changes seen on a Pap test are generally CIN 1. HSIL changes seen on a Pap test can be CIN 2, CIN2/3, or CIN 3.

2025年2月4日 · How is the diagnosis of high grade squamous intraepithelial lesion made? HSIL is usually first detected through a Pap test (Pap smear), a screening test that checks for abnormal squamous cells in the cervix. If HSIL is suspected, further tests may be …

Most distinguishing feature of AIS cells is palisading with nuclear feathering (better seen in Pap-stained direct smears). Without these features, the hyperchromatic cluster under examination may resemble HSIL, especially in LBC preparations

Pap smears screen for cervical cancer. They can also help detect vulvar and vaginal cancer s. Anal Pap smears test the anus for dysplasia and cancer. Colposcopy is a special type of examination for your cervix, vulva and vagina that your provider may use if a Pap smear shows SIL or evidence of the HPV virus.

2025年1月1日 · Diagnosis of HSIL involves a Pap smear or HPV test, followed by colposcopy and biopsy to confirm the presence of abnormal cells. Treatment options for HSIL include watchful waiting, excisional procedures, and ablative techniques to remove or destroy abnormal cells.

2022年1月18日 · Cervix - HSIL cytology: changes in squamous cells associated with HPV, encompassing clinically actionable lesions previously referred to as moderate dysplasia, severe dysplasia, cervical intraepithelial neoplasia 2, CIN 3 and carcinoma in situ

HSIL – high-grade dyskaryosis. (a) Separated cells in a conventional smear showing a streak of separated cells showing the typical features of high-grade dyskaryosis: irregularly dispersed chromatin and nuclear outlines, immature cytoplasm; NC ratio variable but well over 50% in …

What is High Grade Squamous Intraepithelial Lesion (HGSIL)? High grade squamous intraepithelial lesion or HSIL is a finding on the cervical tissues following a Pap smear. HSIL is a type of cervical dysplasia found in microscopic analysis of the cervical cells.