Hsp90 (heat shock protein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in protein degradation. It also stabilizes a …

近期，一篇发表于 Cell Death & Disease 的文章阐述了热休克蛋白 90（HSP90 ）作为多种 程序性细胞死亡 （PCD）常见调控节点的可能性，为众多疾病的治疗贡献了新视角。

2017年4月21日 · The heat shock protein 90 (HSP90) chaperone machinery is a key regulator of proteostasis under both physiological and stress conditions in eukaryotic cells.

HSP90 proteins take part in essential cellular processes and regulatory pathways like apoptosis, cell cycle control, cell viability, protein folding and degradation, and signalling events. In …

2018年8月29日 · The mammalian HSP90 family of proteins is a cluster of highly conserved molecules that are involved in myriad cellular processes. Their distribution in various cellular …

The cytosolic P. falciparum Hsp90 (PfHsp90) is a pivotal player in the development of the parasite, particularly during its intra-erythrocytic stage within the human host. 99 Protozoans, …

2023年6月15日 · The central eukaryotic molecular chaperone Hsp90 physically interacts with a large fraction of the yeast proteome by targeting select intrinsically disordered regions (IDRs) …

2004年3月26日 · The 90 kDa heat shock protein, Hsp90, is a main functional component of an important cytoplasmic chaperone complex, and it is involved in various cellular processes, …

2023年7月31日 · We discuss how these HSP90 forms are shaped by post-translational modifications (PTMs), co-chaperones and other factors, and present evidence for HSP90 …

2025年3月18日 · Hsp90, or heat shock protein 90, a well-preserved molecular chaperone that is essential for the coordination of numerous biological pathways and cellular processes. Hsp90 …