Microtubule-associated protein 2 is a protein in humans that is encoded by the MAP2 gene. [5][6] This gene encodes a protein that belongs to the microtubule-associated protein family.

2025年3月8日 · Angiotensin II Induces Differentiation of Human Neuroblastoma Cells by Increasing MAP2 and ROS Levels. The Cytoskeletal Elements MAP2 and NF-L Show Substantial Alterations in Different Stroke Models While Elevated Serum Levels Highlight Especially MAP2 as a Sensitive Biomarker in Stroke Patients.

Microtubule-associated protein 2 (MAP2) is the predominant cytoskeletal regulator within neuronal dendrites, abundant and specific enough to serve as a robust somatodendritic marker. It influences microtubule dynamics and microtubule/actin ...

2024年12月25日 · MAP2 (Microtubule Associated Protein 2) is a Protein Coding gene. Diseases associated with MAP2 include Central Neurocytoma and Olivopontocerebellar Atrophy. Among its related pathways are TGF-Beta Pathway and CNTF Signaling. Gene Ontology (GO) annotations related to this gene include structural molecule activity and calmodulin binding.

2024年1月24日 · Here, we report several cryo-EM structures of human and fungal MAP2 at the 80S ribosome. Irrespective of nascent chains, MAP2 can occupy the tunnel exit.

Microtubule-associated proteins (MAPs) are a family of proteins that influence this property. We showed previously that MAP2, a neuron-specific protein that stabilizes microtubules in the dendrites of postmitotic neurons, is induced in primary cutaneous melanoma but is absent in metastatic melanomas.

Microtubule-associated protein 2 (MAP2), a neuron-specific protein, stabilizes microtubules and is critical for neurite outgrowth and dendrite development. Although MAP2 is widely used as a marker of neuronal differentiation, regulation of its transcription has not been investigated.

The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.

2023年5月31日 · Three microtubule-associated proteins (MAPs), MAP2, MAP4, and tau 4, 5, 6, 7, 8, which are the most well-studied mammalian-derived MAPs with similar primary structures, promote microtubule...

Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.