2021年11月1日 · Stable isotope labelled oral glucose tolerance tests (siOGTTs; [6,6- 2 H 2]glucose) were performed in both human and mouse cohorts to provide greater resolution into postprandial glucose kinetics. The siOGTT allows for the partitioning of circulating glucose into that derived from exogenous and endogenous sources.

IGT is defined on the basis of an abnormal OGTT. Persons without diabetes but with an OGTT 2-hour value of 140-199 mg/dL are considered to have IGT. Recent national and international randomized controlled trials have shown that diabetes can be delayed or prevented among persons with IGT.

2008年5月1日 · It has been proposed that in early stages of glucose metabolism dysregulation, fasting and 2-h plasma glucose measures during an oral glucose tolerance test (OGTT) may be normal or slightly elevated, but the amount of insulin necessary to maintain this equilibrium is supra-physiological . This state of “insulin resistance” may have ...

Oral glucose tolerance test (OGTT) is traditionally used to define glucose tolerance status based on 2-hour plasma glucose level. There is growing evidence that glucose curve characteristics, such as time of the glucose peak and shape of the glucose curve, may serve as indicators of beta-cell dysfunction.

Objective: The oral glucose tolerance test (OGTT) classifies subjects as normal, glucose intolerant or diabetic depending on glycemia at 120 min (T120) post-test. Five insulin profiles associated with different incidences of diabetes over 10 years' follow-up were previously described following OGTT.

2015年9月22日 · 口服糖耐量试验（OGTT）是口服一定量的葡萄糖后 2 h 内做系列血浆葡萄糖浓度测定，是评价个体血糖调节能力的标准方法，并可了解胰岛 β 细胞的功能。 OGTT 在内分泌科用得非常多，是很基础必会的一项试验。 特撰此文，「一文就会」。 目前 WHO 推荐的标准化方法为受试者在试验前 3 天正常活动，且每天食物中糖含量不低于 150 g，并停用可以影响血糖的药物。 在准备测试的前 10 h 禁食，然后在患者平静时饮入 250 mL 含 75 g 无水葡萄糖的糖水（孕 …

We examined the glucose response curves (biphasic [BPh], monophasic [MPh], incessant increase [IIn]) during an oral glucose tolerance test (OGTT) and their relationship to insulin sensitivity (IS) and β-cell function (βCF) in youth versus adults ...

Methods: Stable isotope labelled oral glucose tolerance tests (siOGTTs; [6,6-2 H 2]glucose) were performed in both human and mouse cohorts to provide greater resolution into postprandial glucose kinetics. The siOGTT allows for the partitioning of circulating glucose into that derived from exogenous and endogenous sources.

2023年12月18日 · Oral glucose tolerance tests (OGTT) are done to measure how well the body can process larger amounts of sugar. If the blood sugar reading is above a certain level, this could be a sign that sugar is not being absorbed fast enough by the body’s organs.

Stable isotope labelled oral glucose tolerance tests (siOGTTs; [6,6- 2 H 2]glucose) were performed in both human and mouse cohorts to provide greater resolution into postprandial glucose kinetics. The siOGTT allows for the partitioning of circulating glucose into that derived from exogenous and endogenous sources.