
Oxidative Stress Markers in Inflammatory Bowel Diseases: …
Precise diagnostic biomarker in inflammatory bowel diseases (IBD) is still missing. We conducted a comprehensive overview of oxidative stress markers (OSMs) as potential diagnostic, …
Oxidative Stress and Redox-Modulating Therapeutics in Inflammatory ...
2020年11月1日 · Oxidative stress is a key feature of Inflammatory Bowel Disease (IBD). However, there is still insufficient understanding of the redox architecture that defines the pathogenic …
Science Advances | 上海交通大学发现炎症性肠病的潜在治疗新方 …
由于零价钼原子的强还原作用,zvmns 可以有效清除 ros 并重塑硫酸葡聚糖钠 (dss) 诱导的 ibd 小鼠模型中的炎症微环境。 体外和体内实验都证实了 ZVMNs 的治疗效果。
ACS Nano | 联硒透明质酸纳米抗氧化剂清除ROS缓解结肠炎- X …
2022年8月24日 · 活性氧(ROS)的过度产生是炎症性肠病(IBD)的一个重要病理特征,是导致信号转导失调、炎症反应和DNA损伤的直接诱因。 ROS过度堆积是IBD病理过程中的核心环节,直 …
Pathomechanisms of Oxidative Stress in Inflammatory Bowel …
This review highlights the generation of reactive oxygen species (ROS) and antioxidant defense mechanisms in the gastrointestinal (GI) tract, the involvement of oxidative stress signaling in …
DNA Nanostructures Treat Inflammatory Bowel Disease through ROS …
2024年5月7日 · This nanostructure demonstrates efficacy in eliminating ROS within cells closely associated with IBD, diminishing inflammation, and ameliorating disorders in gut microbiota, as …
Nano Res. [生物]│袁弘教授课题组:靶向发炎结肠的ROS响应性纳 …
2024年2月29日 · 炎症性肠病(ibd)是一种慢性复发性炎症性疾病包括克罗恩病(cd)和溃疡性结肠炎(uc)。ibd的病因复杂不明,与多种致病因素有关,主要包括遗传因素、肠道菌群失调、 …
An orally administered gold nanocluster with ROS scavenging for ...
2025年1月1日 · Oxidative stress that is induced by excessive reactive oxygen species (ROS) is considered to be a key pathophysiological mechanism of inflammatory bowel disease (IBD), …
The emerging role of oxidative stress in inflammatory bowel disease
Oxidative stress caused by ROS overproduction can contribute to the pathogenesis of IBD by damaging cellular components, activating proinflammatory signaling pathways, and impairing …
Precision therapeutics for inflammatory bowel disease: advancing ROS …
2025年2月5日 · This review discusses the application of various ROS-responsive nanomaterial delivery systems in IBD therapy, highlights current challenges, and outlines future research …