2023年8月15日 · 人类卵胞质内单精子注射（intracytoplasmic sperm injection， ICSI）技术开展至今已有30余年。 其最初主要应用于针对严重少、弱、畸形精子症导致的男性不育患者的治疗，但随着未成熟卵体外培养、卵子冷冻、胚胎植入前遗传学检测等辅助生殖技术的开展， ICSI使用比例已大幅提升。 虽然目前ICSI技术相对成熟，但仍有很多细节值得关注和完善。 为规范与优化人类辅助生殖技术从业者的ICSI操作，由中国医师协会生殖医学专业委员会发起，并联合全国多家生 …

Purpose: Zona pellucida (ZP)-bound sperm used for intracytoplasmic sperm injection (ICSI) enhances embryo quality, implantation, and clinical pregnancy rates. This study aimed to assess the pregnancy outcomes and clinical significance of ICSI with ZP-bound sperm.

The aim of this study was to evaluate whether ZP-binding sperm selection may represent a method to retrieve superior spermatozoa for intracytoplasmic sperm injection (ICSI). Patients were divided into two groups: a ZP-ICSI and a conventional ICSI group.

zp-icsi作为一种模拟生理状态来筛选正常的精子的方法，可以改善icsi的妊娠结局，尤其适用常规icsi反复失败、受精率低、精子严重畸形或dna损伤的病例。

2020年8月21日 · In the present study, we hypothesized that oocyte ZP mechanics correlates with implantation rate. A computational methodology was used to calculate the mechanical parameters that govern ZP...

Intracytoplasmic sperm injection (ICSI / ˈɪksi / IK-see) is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus.

The aim of this study was to evaluate whether ZP–binding sperm selection may represent a method to retrieve superior spermatozoa for intracytoplasmic sperm injection (ICSI). Patients were divided into two groups: a ZP-ICSI and a conventional ICSI group.

本共识将从ICSI的适应证、正常及常见异常形态卵子、卵子的显微注射、受精观察、ICSI特殊情况的应对及其他细节、ICSI技术的质控及培训等几个方面进行阐述并提出相应推荐意见，旨在为人类ART实验室从业者提供实用性参考，从而为广大不孕患者提供更高质量的服务。 虽然ICSI技术成功解决了一些严重男性因素导致的不孕问题，但在部分非男性因素不孕的治疗方面，其有效性和安全性仍不明确 [ 3, 4 ]。 因此，ICSI技术的使用需更加谨慎。 1.男性因素：①极重度少精子症及 …

In the current study, we evaluated the ability of the ZP of immature oocytes to harvest the fittest sperm. We compared the embryological outcomes of intracytoplasmic sperm injection (ICSI) using conventionally selected sperm (control group) and ZP-bound sperm (intervention group).

ICSI transformed the field of reproductive technology by offering men with severe sperm problems their first opportunity to have children. The technique involves using a microscope to visualize the sperm. An embryologist selects a single live sperm in …