Interferons (IFN s, / ˌɪntərˈfɪərɒn / IN-tər-FEER-on[1]) are a group of signaling proteins [2] made and released by host cells in response to the presence of several viruses. In a typical scenario, a virus-infected cell will release interferons causing nearby cells to heighten their anti-viral defenses.

2019年8月2日 · Mechanistically, IFN-β overrides pro-survival cues and promotes apoptosis in murine and human neutrophils through STAT3 activation, and enhances efferocytosis by resolution phase macrophages,...

2023年3月28日 · 干扰素β (Interferon-β,IFN-β)是由 成纤维细胞, 白细胞 等产生的一种微量,高效的细胞因子，属 Ⅰ型干扰素，由成纤维细胞等多种细胞在病毒、核酸等诱导后产生，与α干扰素结合相同的受体，具有相似生物学作用。

干扰素 （interferon，IFN [1]）是一组具有抗病毒活性、抗肿瘤、免疫调节、维持细胞自身稳定等多种生物学活性功能的 糖蛋白 [2]。 干扰素最初发现的功能是可干扰多种病毒的复制，因而得名。 干扰素也最早被发现的 细胞因子，具有 细胞信号传送 作用 [3]。

2024年12月25日 · IFNB1 (Interferon Beta 1) is a Protein Coding gene. Diseases associated with IFNB1 include Multisystem Inflammatory Syndrome In Children and Secondary Progressive Multiple Sclerosis. Among its related pathways are Overview of interferons-mediated signaling pathway and SARS-CoV-2 Infection.

IFN-γ是Ⅱ型干扰素家族的唯一成员，主要由T淋巴细胞、自然杀伤细胞和抗原提呈细胞（APCs）如单核细胞、巨噬细胞和树突状细胞分泌。 IFN-γ的产生受抗原呈递细胞分泌的细胞因子控制，尤其是IL12和IL18。

2005年5月1日 · There are two main classes of interferon (IFN): type I IFNs and type II IFN. There are many type I IFNs, including IFN-α, IFN-β and IFN-ω, and all of these bind a common cell-surface...

IFN（干扰素）是抵御病毒感染的第一道防线中的强效细胞因子和关键组分 1，主要通过直接诱导可抑制病毒复制的抗病原体分子对抗措施实现炎症和免疫控制 2。

2012年3月13日 · Here, we review the functions of IFN-β in innate and adaptive immunity. We also discuss the activation and influence of IFN-β on myeloid cell types, including monocytes and dendritic cells, as well as address the effects of IFN-β on T cells and B cells.

It is now known that type I IFNs (IFNα and IFNβ) are the major contributors in innate immunity serving as the first line of defense against viruses. They are more than just anti-virals as they play a major role in linking innate to adaptive immunity.