igfbp-3是出生后血液中含量最丰富的一种igf结合蛋白。 它与IGF结合，防止它们被降解，促进IGF在身体各部分的运输，对IGFs结构进行修饰从而改变IGFs与其特异性受体之间的相互作用。

Insulin-like growth factor-binding protein 3 (IGFBP-3) is a 264-amino acid peptide (molecular weight 29 kDa) produced by the liver.

Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six IGF binding proteins (IGFBP-1 to IGFBP-6) that have highly conserved structures and bind the insulin-like growth factors IGF-1 and IGF-2 with high affinity.

2020年11月25日 · igfbp-3是出生后血液中含量最丰富的一种igf结合蛋白。 它与IGF结合，防止它们被降解，促进IGF在身体各部分的运输，对IGFs结构进行修饰从而改变IGFs与其特异性受体之间的相互作用。

Elevated levels of Insulin-like Growth Factor Binding Protein 3 (IGFBP-3) can be indicative of various health conditions, particularly related to growth and cancer risk. IGFBP-3 is a protein that helps regulate the actions of insulin-like growth factors, which are …

胰岛素样生长因子结合蛋白-3与生长激素关系密切，是筛查生长激素缺乏症有的良好指标，被用来监测5岁以内的生长激素缺乏的情况；当胰岛素样生长因子结合蛋白-3增加时，对肢端肥大症有一定提示作用；胰岛素样生长因子结合蛋白-3水平降低则提示可能有垂体 ...

Elevated IGF-1 and IGFBP-3 levels support the diagnosis of acromegaly or gigantism in individuals with appropriate symptoms or signs. In successfully treated patients, both levels should be within the normal range, ideally within the lower third.

Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3), one of the six members of the IGFBP family, is a key protein in the IGF pathway. IGFBP-3 can function in an IGF-dependent as well as in an IGF-independent manner.

血清IGFBP-3降低常提示生长激素缺乏症，其敏感性可达97%、特异性达95%，是筛查生长激素缺乏症良好的指标。 对于是生长激素缺乏导致的矮小 还是生长激素受体缺陷所致的矮小具有鉴别意义，理论上IGF-1和IGFBP-3的变化应该是一致的，若是出现不一致时提示出现不良反应的风险增加，所以建议有条件的孩子IGF-1、IGFBP-3这两项检查都要做。 本文是彭惠版权所有，未经授权请 …

2024年12月25日 · IGFBP3 (Insulin Like Growth Factor Binding Protein 3) is a Protein Coding gene. Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Laron Syndrome.