CD8α (C8/144B) Mouse mAb recognizes endogenous levels of total CD8 protein. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CD8 protein. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits.

CD8α (C8/144B) Mouse mAb recognizes endogenous levels of total CD8 protein. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human CD8 protein. Cluster of Differentiation 8 (CD8) is a disulphide-linked heterodimer consisting of the unrelated α and β subunits.

Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. Defects in CD8A are a cause of familial CD8 deficiency (CD8 deficiency) [MIM:608957].

Human lymph node, T cell lymphoma: immunohistochemical staining for CD8. Note the neoplastic cells show a moderate to strong, distinct membrane staining reaction. CD8: clone 4B11. The CD8 molecule is composed of two chains and has a molecular weight of 32 kD.

Find the CD8 antibody that fits your needs. Choose from 1 of 597 CD8 antibodies, which have been validated in experiments with 10852 publications and 3438 images featured in our data gallery. Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other...

MA5-14548 targets CD8 in IHC (P), and FACS applications and shows reactivity with Human samples. The MA5-14548 immunogen is synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule.

Monoclonal Antibody for studying CD8A. Validated for F, IHC, IP, WB. Available in 2 sizes. Highly specific and rigorously validated in-house, CD8α (D8A8Y) Rabbit Monoclonal Antibody (CST #85336) is ready to ship.

CD8α antibody for detecting a subset of activated peripheral CD4+ T cells. Validated for WB, IHC, IHC. Available in 2 sizes. Click here to learn more.

CD8-α抗体（C8/144B）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）和石蜡包埋切片免疫组织化学（IHCP）特异性检测人源CD8-α蛋白。

CD8分子由两条链组成，分子量为32kD。 它存在于正常细胞毒性/抑制细胞的T细胞亚群中，其构成人外周血淋巴细胞的约20％至35％。 据报道，CD8抗原在自然杀伤细胞（80％的胸腺细胞），30％的外周血无效细胞和15％至30％的骨髓细胞亚群中被检测到。