IKK-β also known as inhibitor of nuclear factor kappa-B kinase subunit beta is a protein that in humans is encoded by the IKBKB (inhibitor of kappa light polypeptide gene enhancer in B …

IKK（inhibitor of kappa B kinase [2], kappa B 抑制因子激酶）参与胞内多种细胞信号转导途径，包括由 细胞因子 引起的 细胞凋亡,其中最为人熟知的是可以通过磷酸化 细胞质基质 中与 NF-κB …

NF-κB （Nuclear Factor kappa-light-chain-enhancer of activated B cells）通路是一种在细胞信号传递中极为重要的途径，它在 调控免疫反应 、 炎症反应 、 细胞生长与死亡 等多种生理过程 …

2008年4月1日 · IKKβ/IKBKB (IκB kinase beta), also designated as IKK2, was named after its function of phosphorylating IκB molecules, the inhibitors of NF-κB transcription factors.

1997年10月31日 · Two components of the IKK signalsome, IKK-1 and IKK-2, were identified as closely related protein serine kinases containing leucine zipper and helix-loop-helix protein …

2002年4月19日 · IKK-1 and IKK-2 are two direct IkappaB kinases. Two recently identified novel IKKs are IKK-i and TBK-1. We have cloned, expressed, and purified to homogeneity …

Inhibitory kappa B kinase beta (IKKβ), known as IKK2, is a key regulatory kinase responsible for the activation of NF-κB through its phosphorylation at Ser177 and Ser181 to promote the …

2018年5月21日 · Inhibitor kappa B kinase 2 (IKK2) plays an essential role in the activation of nuclear factor kappa B (NF-kB). Recently, it has been suggested that IKK2 acts as a myosin...

IKKbeta/IKBKB (IkappaB kinase beta), also designated as IKK2, was named after its function of phosphorylating IkappaB molecules, the inhibitors of NF-kappaB transcription factors.

2007年1月1日 · Inhibitors of IKK-2, which inhibit signaling in the NF-κB pathway (initiated by TNF-a binding to its receptor), represent potential new drug candidates, as shown by the …