IL-7和IL-7R的生物学和临床应用 - 知乎 - 知乎专栏
IL-7 是一种由 IL7 基因编码的25kDa大小的可溶性分泌蛋白，其受体（IL-7R）是一种异二聚体复合物，由IL-7Rα和γ链组成，γ链与IL-2、IL-4、IL-7、IL-9、IL-15和IL-21的受体共享。 IL-7及其 …
认识明星小分子：IL-7 - 知乎 - 知乎专栏
il-7通过调节免疫细胞释放ifn-γ、il-1β、il-1α和tnf-α等细胞因子发挥抗肿瘤作用。相反，il-7可以通过与il-7r结合激活jak/stat5、pi3k/akt和ras/erk信号通路来调节bcl-2、bcl-xl基因表达水平，从而 …
Interleukin-7 receptor - Wikipedia
Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others. Interleukin-7 receptor has been shown to play a critical role in the development …
IL7R Gene - GeneCards | IL7RA Protein | IL7RA Antibody
2024年12月25日 · IL7R (Interleukin 7 Receptor) is a Protein Coding gene. Diseases associated with IL7R include Immunodeficiency 104, Severe Combined and T-B+ Severe Combined …
Flip the coin: IL-7 and IL-7R in health and disease - Nature
2019年11月19日 · In this Review, we examine the physiology and pathophysiology of IL-7 and IL-7R, with particular emphasis on their involvement in the promotion of cancer, for which there is …
健康与疾病中的IL-7和IL-7R - 知乎 - 知乎专栏
il-7和il-7r参与结肠慢性炎症与以下观点一致：转移性结直肠癌患者显示高il-7水平，并且癌组织本身可以分泌il-7。 IL-7R介导的实体癌中潜在的促肿瘤功能。
IL-7: Comprehensive review - ScienceDirect
2022年12月1日 · IL-7 has been evaluated in patients with cancer and shown to expand lymphocytes. It accelerated lymphocyte recovery after hematopoietic stem cell transfer, and …
Interleukin-7 receptor expression: intelligent design - Nature
The interleukin-7 receptor (IL-7R) consists of two chains, the IL-7R α-chain (IL-7Rα; also known as CD127) and the common cytokine-receptor γ-chain (γ c; also known...
Frontiers | Interleukin-7 Biology and Its Effects on Immune Cells ...
2021年12月1日 · Interleukin-7 (IL-7), a molecule known for its growth-promoting effects on progenitors of B cells, remains one of the most extensively studied cytokines. It plays a vital …
IL-7和IL-7R的生物学和临床应用 - 健康界
2022年8月17日 · IL-7是一种由IL7基因编码的25kDa大小的可溶性分泌蛋白，其受体（IL-7R）是一种异二聚体复合物，由IL-7Rα和γ链组成，γ链与IL-2、IL-4、IL-7、IL-9、IL-15和IL-21的受体 …