Pathology Outlines - INI1 / SMARCB1
2022年6月1日 · SMARCB1 (SWI / SNF related, matrix associated, actin dependent regulator of chromatin subfamily B member 1), INI1 (integrase interactor 1), BAF47, hSNF5
INI1-deficient tumors: diagnostic features and molecular genetics
We will review the clinicopathologic features of these tumor types and emphasize the clinical utility of INI1 immunohistochemistry in differential diagnosis. Significant progress has been made in …
SMARCB1 - Wikipedia
SWI/SNF -related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 is a protein that in humans is encoded by the SMARCB1 gene. [5][6][7] The protein encoded …
【衡道丨笔记】病例分享 ：SMARCB1/INI1缺失相关肿瘤|免疫组 …
2022年6月14日 · smarcb1/ini1是抑癌基因，位于染色体22q11.23，编码蛋白认为是swi/snf染色质重塑复合物的一种核心亚基，在所有正常细胞的细胞核中广泛表达，是细胞分化期间转录程序 …
INI1（SMARCB1）缺失性肺癌1例 - 中华病理学杂志 - Yiigle.com
INI1（SMARCB1）蛋白是染色体重塑相关多聚体蛋白SWI/SNF的一个亚单位，SWI/SNF复合体缺失的未分化癌对传统化疗药物不敏感、预后差，但组蛋白甲基转移酶抑制剂治疗可能有效，而 …
Oncogenic roles of SMARCB1/INI1 and its deficient tumors
SMARCB1/INI1 is one of the core subunit proteins of the ATP‐dependent SWI/SNF chromatin remodeling complex, and is identified as a potent and bona fide tumor suppressor. Interactions …
SMARCB1/INI1-deficient tumors of adulthood - PMC - PubMed …
2020年6月30日 · SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1), also known as integrase interactor 1 (INI1), is a crucial …
SMARCB1基因缺失与胰腺癌 - 知乎 - 知乎专栏
2023年11月10日 · SMARCB1/INI1缺陷胰腺未分化横纹肌样癌是一种非常具有侵袭性的肿瘤，文献中很少报道。 肿瘤有主要的横纹肌细胞成分和不同的生长模式已被报道。 一名59岁女性，表 …
儿童INI1基因缺失性肿瘤研究进展 - 中华儿科杂志
整合酶相互作用因子1（integrase interactor 1，INI-1）是染色质重塑复合物SWI/SNF的核心亚基，位于染色体22q11.2位置，是基因表达和细胞分化的重要调节因子，于20世纪90年代首次在 …
SMARCB1 (INI-1)-Deficient Sinonasal Carcinoma: A Systematic …
SMARCB1 (INI1) is a core subunit of the SWItch/sucrose non-fermentable (SWI/SNF) complex mapped to chromosomal region 22q11.23. Though many SWI/SNF protein subunits are …