Purpose: To investigate the relationship between the single-point insulin sensitivity estimator (SPISE) index, an insulin sensitivity indicator validated in adolescents and adults, and metabolic profile in overweight/obese children, and to evaluate whether basal SPISE is predictive of impaired glucose regulation (IGR) development later in life.

2023年2月8日 · Background: The Single-Point Insulin Sensitivity Estimator (SPISE) is a biomarker of insulin sensitivity estimated using BMI and triglycerides and high-density lipoprotein cholesterol. We assessed the accuracy of SPISE to screen obesity-related cardiometabolic risk in …

The Single-Point Insulin Sensitivity Estimator (SPISE) is a biomarker of insulin sensitivity estimated using BMI and triglycerides and high-density lipoprotein cholesterol. We assessed the accuracy of SPISE to screen obesity-related cardiometabolic ...

2024年11月21日 · SPISE index is a promising predictor of insulin resistance, as it requires only a single fasting blood sample and could be a possible tool for large-scale population screening to identify individuals at higher risk of cardiovascular disease.

2024年11月22日 · The SPISE index, based on values of fasting triglycerides (mg/dL), HDL cholesterol (mg/dL), and BMI (kg/m2), shows promise in predicting insulin resistance in children.

Background: Insulin resistance in children and adolescents with obesity is linked to increased risk of type 2 diabetes mellitus and cardiovascular disease. The SPISE index, based on values of fasting triglycerides (mg/dL), HDL cholesterol (mg/dL), and BMI (kg/m2), shows promise in predicting insulin resistance in children.

2019年11月7日 · We intended to analyze a new recently presented fasting index, SPISE (sensitivity formula: 600 × HDL-cholesterol 0.185 /triglycerides 0.2 /BMI 1.338), in comparison with three previously known fasting indexes, regarding correlation with the insulin clamp index, and for the predictive effects of future long-term risks of coronary heart disease (C...

spise可能被认为是一种相对简单且低成本的诊断工具，有助于识别具有较大生物学风险的患者。 在肥胖青少年中，相同的切点可以识别出 IR 和 MetS 风险较高的人群。

2021年6月17日 · Among the non-insulin-derived indices, the single-point insulin sensitivity estimator (SPISE) index is a lipids and BMI-based index of insulin sensitivity that showed better accuracy than other indicators, such as its forerunner TG/HDL-C ratio and HOMA-IR, in the prediction of metabolic syndrome and has been recently validated in adolescents and...

2019年11月7日 · We intended to analyze a new recently presented fasting index, SPISE (sensitivity formula: 600 × HDL-cholesterol0.185/triglycerides0.2/BMI1.338), in comparison with three previously known fasting...