Ionized calcium-binding adaptor molecule 1 (Iba1), also known as allograft inflammatory factor 1 (AIF-1), is an evolutionarily conserved cytoplasmic calcium binding protein containing a central pair of EF-hand calcium binding motifs (1,2).

Iba1靶点介绍 蛋白功能. Iba1（离子钙结合适配器分子1），也称为同种异体移植炎症因子1（AIF1），是一种进化上保守的细胞浆钙结合蛋白。 Iba1是细胞骨架结合蛋白，促进细胞膜运动与RAC激活，并在RAC信号通路及吞噬过程中发挥作用。

Allograft inflammatory factor 1 (AIF-1) also known as ionized calcium-binding adapter molecule 1 (IBA1) is a protein that in humans is encoded by the AIF1 gene. [5][6] The AIF1 gene is located within a segment of the major histocompatibility complex class III region.

Fujifilm Wako’s "Anti Iba1, Rabbit (for immunocytochemistry)" (Product Number 019-19741), which allows even microglia processes to be stained by immunohistochemical staining, is used by researchers all over the world as a microglia marker antibody standard.

IBA1/AIF-1 是一种进化上保守的钙结合蛋白。 作为 F-肌动蛋白结合蛋白，Iba1/AIF-1 可能会重塑小胶质细胞的肌动蛋白细胞骨架。 Iba1/AIF-1 在单核细胞谱系的细胞中独特表达，因此，靶向该蛋白的抗体被广泛用于标记大脑和其他组织中的小胶质细胞/巨噬细胞。 Iba1/AIF-1 (E4O4W) XP® Rabbit mAb #17198： 使用 Iba1/AIF-1 (E4O4W) XP ® Rabbit mAb #17198（绿色）对人皮层（左图）和小鼠 CA1 海马（右图）进行共聚焦免疫荧光分析。 在小鼠组织切片中，细胞核标有 …

Iba1，离子钙结合适配器分子 1，也称为同种异体移植炎症因子1 (AIF1)，是一种进化上保守的细胞浆钙结合蛋白。 Iba1是细胞骨架结合蛋白，促进细胞膜运动与RAC激活，并在RAC信号通路及吞噬作用中发挥作用。

6 天之前 · Ionized calcium-binding adaptor molecule 1 (Iba1), also known as allograft inflammatory factor 1 (AIF-1), is an evolutionarily conserved cytoplasmic calcium binding protein containing a central pair of EF-hand calcium binding motifs (1,2).

2023年7月27日 · Iba1 Antibody (1022-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects Iba1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and flow …

Iba1 Monoclonal Antibody detects endogenous levels of Iba1 protein. Fig : Western blot analysis of IBA1 on different lysates. Proteins were transferred to a NC membrane and blocked with 5% NF-Milk in TBST for 1 hour at room temperature. The primary antibody (AWA06005, 1/1000) was used in TBST at room temperature for 2 hours.