Because phosphorylation of the infectious bronchitis virus (IBV) nucleocapsid protein (N) may regulate its multiple roles in viral replication, the dynamics of N phosphorylation were examined. 32P-orthophosphate labeling and Western blot analyses ...

In this study, the proteome of the IBV strain Beau-R virion was investigated using gel-free liquid chromatography-coupled mass spectrometry (MS) methods. The Beau-R strain of IBV is a molecular clone of the Beaudette strain, which grows to high titres in embryonated chicken eggs, making it ideal for this study.

2009年3月16日 · The M protein is integrated into the viral envelope with three transmembrane domains flanked by a short amino-terminal ectodomain and a large carboxy-terminal endodomain. In this study, we showed co-purification of the M protein from coronavirus infectious bronchitis virus (IBV) with actin.

2020年1月24日 · Using these five rIBVs, we have shown that, although not essential for intracellular genome replication and virion assembly, the EIC of IBV is required for the efficient release of infectious virions and viral fitness in vitro. It is also required for the activation of ER stress and induction pro-inflammatory cytokines during the late stage of ...

2025年2月25日 · Here, we demonstrate that the infectious bronchitis virus (IBV) S protein directly interacts with coatomer protein-I (COPI)-coated vesicles through the KKSV motif in its cytoplasmic tail. COPI-coated vesicles mediate the retrograde transport of S protein from the Golgi apparatus to the endoplasmic reticulum-Golgi intermediate compartment, where ...

Infectious bronchitis virus (IBV) is caused by avian coronavirus and poses a global economic threat to the poultry industry. In 2023, a highly pathogenic IBV strain, IBV/CN/GD20230501, was isolated and identified from chickens vaccinated with IBV-M41 in Guangdong, China.

Infectious bronchitis is a highly contagious respiratory disease of poultry caused by the coronavirus infectious bronchitis virus (IBV). It was thought that coronavirus virions were composed of three major viral structural proteins until investigations of other coronaviruses showed that the virions …

2025年1月22日 · Our previous studies demonstrated that truncation of 9 amino acids in the cytoplasmic tail (CT) of the infectious bronchitis virus (IBV) spike (S) protein impairs its localization to the ERGIC, resulting in increased expression at the plasma membrane. However, the precise mechanism underlying this phenomenon remained elusive.

2016年11月23日 · Avian coronavirus infectious bronchitis virus (IBV) is a member of Coronaviridae family, and the virus is responsible for infectious bronchitis, an acute, highly...

2015年12月1日 · In this study, the proteome of the IBV strain Beau-R virion was investigated using gel-free liquid chromatography-coupled mass spectrometry (MS) methods. The Beau-R strain of IBV is a molecular clone of the Beaudette strain, which grows to high titres in embryonated chicken eggs, making it ideal for this study.