2019年5月7日 · In these cases, when ICM+® indicates that the zone of optimal CPP might lie outside the 60–70 range, this can be interpreted as a clinical predictor of a potentially successful ABP challenge. This relatively simple test can be performed by an experienced intensivist, at the bedside, provided caution is applied when leaving the CPP range of ...

2010年3月1日 · ICM + software encapsulates our 20 years' experience in brain monitoring. It collects data from a variety of bedside monitors and produces time trends of parameters defined using configurable mathematical formulae.

2019年4月25日 · added. Dynamic CAR is monitored using ICM+® software, recognizing the limitations described above [14]. We con-sider an ABP challenge as second-tier therapy for isolated elevated ICP, or for intracranial hypertension combined with low PbtO 2, only after correction of other first-tier level factors [15]. In these cases, when ICM+® indicates

2023年5月20日 · We aim to validate this in a large multicentre cohort. Recordings from 171 TBI patients from the high-resolution cohort of the CENTER-TBI study were processed with ICM+ software. We derived LLR as a time trend of CPP at a level for which the pressure reactivity index (PRx) indicates impaired cerebrovascular reactivity with low CPP.

approach. Details on the exact ICM+ settings and calcu-lation methods can be found in the COGiTATE protocol paper by Beqiri et al. [16]. In short, a 5-min median CPP time trend was calculated along the PRx (Fisher trans-formed to achieve normal distribution) and these PRx values were grouped into CPP bins of 5mmHg (within 40–120mmHg range).

2008年3月13日 · All signals were digitised, and recorded using ICM+ software. We divided the events into two groups, depending on whether ABP (Group 1) or ICP (Group 2) was the first parameter to change. Group 1 was further subdivided based on whether the vascular autoregulation was intact (ABP-ICP negative correlation) or was impaired (ABP-ICP positive ...

2009年3月13日 · A prospective observational study of 20 patients with TBI at the Royal London Hospital. All patients were managed according to the local guidelines for the management of TBI. PRx was determined by ICM+ (Cambridge University) software by calculating the correlation coefficient between ICP and arterial blood pressure.

2013年3月19日 · Twenty-one TBI patients admitted to the university hospitals of Leuven, Belgium and Tubingen, Germany were continuously monitored using ICM+ software (Cambridge Enterprise) allowing for continuous PRx calculation.

variables to the ICM+ software (Cambridge Enterprise Ltd., Cambridge, UK). More recently, based on ICP waveform peak relationship changes following cerebral compliance status, Brasil et al. observed the P2/P1 ratio (the second peak amplitude elevation) and time-to-peak (the time length from pulse triggering to its highest peak

2024年9月4日 · All post-acquisition signal processing was performed using ICM+ software. To ensure quality of raw data, signal artifacts were removed by qualified personnel without knowledge of the study objectives or patient demographics. This involved removing segments of data that lacked proper waveform morphology or had implausibly high/low values.