Serum regulation of Id1 expression by a BMP pathway and BMP …
The Id1 BRE is necessary and sufficient for the serum regulation of Id1. Inhibition of the BMP pathway by siRNA depletion of Smad 4, treatment with the BMP antagonist noggin, or the …
Identification of a BMP-responsive element in Id1, the gene for ...
Background: Bone morphogenetic protein-2 (BMP-2) stimulates osteoblast differentiation, but inhibits myogenic differentiation in C2C12 myoblasts. BMP-2 induces transcription of Id1, an …
Id: A Target of BMP Signaling | Science's STKE - AAAS
2002年9月24日 · BMP-2 induces expression of Id1 and Id3 in neuroepithelial cells, which occurs in a Smad-dependent manner. Both Id1 and Id3 repress the promoter activation induced by …
Serum regulation of Id1 expression by a BMP pathway and BMP …
AZD0530 inhibits the constitutive activation of the Id1 promoter by type 1 BMP receptors. Constitutively active type 1 BMP receptors, ALK1 to 5 and ALK7 were transfected with the Id1 …
BMP蛋白通路检测与Noggin蛋白活性检测 - 知乎 - 知乎专栏
id1启动子序列是bmp信号通路的下游响应元件。 报告基因质粒是将 Smad结合元件 Id1启动子序列装在荧光素酶启动子位置。 一旦BMP-Smad通路被激活，报告基因就会表达荧光素酶，通过 …
Id proteins are critical downstream effectors of BMP signaling in …
2013年8月15日 · In conclusion, Id proteins, and particularly Id1 and Id3, are critical downstream effectors of BMP signaling in PASMCs. Loss of BMPR-II function reduces the induction of Id …
Rare but specific: 5-bp composite motifs define SMAD binding in BMP …
5 天之前 · This finding is consistent with the higher BMP sensitivity observed in ID1- and ID3-Luc reporters, both featuring a Gua at the + 3 position, compared to our GC-poor linker (Fig. 3a). …
Control of neuronal excitation–inhibition balance by BMP–SMAD1 ...
2024年4月17日 · We combined BMP-response element sequences (4×BRE) from the Id1 promoter 32 with the small molecule (LMI070)-gated miniX on cassette 33 to drive a nucleus …
ID1-Mediated BMP Signaling Pathway Potentiates Glucagon-Like …
Given that bone morphogenetic protein (BMP) is a unique extracellular multifunctional signaling molecule belonging to the TGF-β superfamily , gene set enrichment analysis (GSEA) revealed …
Id1 and Id3 Are Regulated Through Matrix‐Assisted Autocrine BMP ...
The resulting locally increased BMP concentrations at the cell surface may thereby become sufficient to induce autocrine BMP-mediated Id1 and Id3 expression. To test this hypothesis, …