BMP signaling is responsible for serum-induced Id2 expression
2012年4月6日 · A small-molecule inhibitor of bone morphogenetic protein (BMP) type I receptor kinases blocked the serum induction of Id2 mRNA. The chemical compound and several …
Id: A Target of BMP Signaling | Science's STKE - AAAS
2002年9月24日 · BMP-2 induces expression of Id1 and Id3 in neuroepithelial cells, which occurs in a Smad-dependent manner. Both Id1 and Id3 repress the promoter activation induced by …
BMP4/Id2 signaling pathway is a novel therapeutic target for late ...
2017年2月1日 · Bone morphogenetic protein 4 (BMP4) is involved in vascular injury-mediated mobilization and homing of LEPCs. Here, we investigated the influence of BMP4-modified …
Id2 和 Id3 定义细胞增殖和分化对转化生长因子 β 和骨形态发生蛋 …
内源性 Id2 或 Id3 的敲低使上皮细胞对 BMP 敏感，从而导致强烈的生长抑制和转分化诱导。 因此，Id 基因感知 Smad 信号并创建一个宽松或难处理的核环境，该环境决定了细胞命运和增殖的 …
Id proteins are critical downstream effectors of BMP signaling in …
2013年8月15日 · Id proteins (Id1-4) are major downstream transcriptional targets of BMP signaling. However, the impact of BMPR-II mutation on the expression of the range of Id …
BMP-Smad-Id2信号通路激活对大鼠神经干细胞分化影响的研究
2020年1月10日 · Id2 作为Id 家族中重要的成员之一其在调节细胞增殖和维持细胞多样性和 分化方面起着至关重要的作用，研究表明脊髓损伤后局部组织内Id2 蛋白表达会 显著增加，这一上升 …
BMP-7/Smads-induced inhibitor of differentiation 2 (Id2
The results showed that bone morphogenetic protein-7 (BMP-7) upregulated the expression of Id2 against high-glucose-induced EMT and extracellular matrix secretion. Moreover, only the …
Id proteins are critical downstream effectors of BMP signaling in …
Our recent study revealed that Id1 and Id2 are induced by BMPs in pulmonary artery smooth muscle cells (PASMCs) through a canonical Smad-dependent pathway and that BMPR-II …
BMP signaling is responsible for serum-induced Id2 expression
2012年4月6日 · A small-molecule inhibitor of bone morphogenetic protein (BMP) type I receptor kinases blocked the serum induction of Id2 mRNA. The chemical compound and several …
BMP-7 Upregulates Id2 Through the MAPK Signaling Pathway to …
2022年6月2日 · Bone morphogenetic protein (BMP)-7 is a negative regulator of organ fibrosis and may also play an essential role in tubulointerstitial fibrosis. This study aimed to investigate the …