IDH3A Gene - GeneCards | IDH3A Protein | IDH3A Antibody
2024年12月25日 · IDH3A (Isocitrate Dehydrogenase (NAD(+)) 3 Catalytic Subunit Alpha) is a Protein Coding gene. Diseases associated with IDH3A include Retinitis Pigmentosa 90 and D …
IDH3A - Wikipedia
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (IDH3α) is an enzyme that in humans is encoded by the IDH3A gene. [5] [6] Isocitrate dehydrogenases (IDHs) catalyze the …
异柠檬酸脱氢酶 (NAD (+) ) 3 催化亚基 α（IDH3A）基因 | MCE
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These Enzymes belong to two distinct subclasses, one of which utilizes NAD (+) as the …
Nuclear localization of mitochondrial TCA cycle enzymes …
2022年12月2日 · The nuclear-localized TCA cycle enzymes Pdha1, Pcb, Aco2, Cs, Idh3a promote somatic cell reprogramming and primed-to-naive transition. In addition, nuclear …
异柠檬酸脱氢酶 3A 是 TCA 循环的限速酶，可通过调节 …
idh3a 轴的鉴定为 hcc 的发病机制提供了新的见解，idh3a 轴可能代表了治疗 hcc 的新靶点。本研究表明，idh3a 可以通过诱导 mta1 表达上调 mta1 表达并促进 hcc 上皮间质转化 (emt)，从而 …
IDH3A isocitrate dehydrogenase (NAD (+)) 3 catalytic subunit …
This study highlights the importance of including this rarely-mutated gene in the molecular diagnostic set-ups for inherited retinal degenerations, and further delineates the phenotypic …
Cell Metabolism丨线粒体异柠檬酸脱氢酶通过抑制抗氧化剂代谢和 …
通过线粒体相关化合物筛选，我们发现美国 FDA 批准的 异柠檬酸脱氢酶 2 （IDH2）抑制剂 enasidenib 可增强记忆 CAR T 细胞的形成，并维持体内抗白血病细胞毒性。 从机理上 …
IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit …
2025年2月9日 · Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD …
The Krebs Cycle Enzyme Isocitrate Dehydrogenase 3A Couples ...
Here, we uncover a role for isocitrate dehydrogenase 3a (idh3a), a Krebs cycle enzyme, in neurotransmission. Loss of idh3a leads to a reduction of the metabolite, alpha-ketoglutarate …
IDH3A基因详情-基因数据库-基因云馆 - Genelibs
IDH3A的详细信息，包括基因名称，代码，染色体位置，相互作用关系和通路，简述为异柠檬酸脱氢酶催化异柠檬酸的氧化脱羧到2-酮戊二酸。 这些酶属于两个不同的亚类，其中一个利 …