Commensal microbes on the skin surface influence the behaviour of cells below the epidermis. We hypothesized that bacteria or their products exist below the

Intestinal commensal bacteria induce protective and regulatory responses that maintain host-microbial mutualism. However, the contribution of tissue-resident

2021年4月5日 · Despite critical functions in cutaneous health and disease, it is unclear how resident skin microbial communities are altered by topical antimicrobial

Skin wounds heal by coordinated induction of inflammation and tissue repair, but the initiating events are poorly defined. Here we uncover a fundamental role of commensal skin microbiota in this process and show that it is mediated by the recruitment and the activation of type I …

2024年11月2日 · In this article, we synthesized metal-peptide colloidal nanohybrids using two chemical components: (1) amphiphilic tripeptide building block (IFH) and (2) silver nitrate (AgNO 3), which has...

2024年10月16日 · A comprehensive multi-omics reference atlas of prenatal human skin shows that innate immune cells crosstalk with non-immune cells to perform pivotal roles in skin morphogenesis, including the...

2022年8月3日 · Aberrant activation of interferon (IFN)-γ signaling plays a key role in several autoimmune skin diseases, including lupus erythematosus, alopecia areata, vitiligo, and lichen planus. Here, we identify fully chemically modified small interfering RNAs (siRNAs) that silence the ligand binding chain of …

2021年12月24日 · The SMGC enables classification of a median of 85% of skin metagenomic sequences and provides a comprehensive view of skin microbiome diversity, derived primarily from samples obtained in North...

2019年5月1日 · Significantly fewer transient and residential bacteria remained on the skin if hands were dried with a jet air dryer (P<0.001). Drying hands with paper towelsincreased the number of resident bacteria, including potentially pathogenic species, released from the volunteers’ skin, compared to a jet air dryer.

2024年12月5日 · Maintaining optimal skin health and function is important for overall health, and modifiable lifestyle factors may impact both skin health and disease. Within the functional medicine framework, practitioners partner with patients to develop personalized treatment plans that best fit each patient’s current conditions and concerns.