1997年10月9日 · The structure of an intact monoclonal antibody for phenobarbital, subclass IgG1, has been determined to 3.2 A resolution by X-ray crystallography. The molecule was …

2016年4月22日 · The crystallizable fragment (Fc) of the immunoglobulin class G (IgG) is an attractive scaffold for the design of novel therapeutics. Upon engineering the C-terminal loops …

2021年1月20日 · Structure of Human IgG1 Fc

2023年3月23日 · In a recent article 9, we used long all-atom molecular dynamics (MD) simulations of the IgG1 b12 crystal structure (PDB ID: 1HZH 10) from the RCSB protein data …

Atomic Coordinate Files for Whole IgG1 This PDB file contains a model of an entire human IgG1 molecule, including carbohydrate. This web site is the first where it was made publically …

2015年5月5日 · Scientific Reports - 3D Structural Fluctuation of IgG1 Antibody Revealed by Individual Particle Electron Tomography. ... PDB was represented by ribbon and chains were …

2016年2月10日 · Schematic representation of homodimeric human IgG1-Fc (PDB-ID 1OQO), generated using PyMOL, with the corresponding amino acid sequence. IgG1 is composed of …

Download scientific diagram | Crystal structure of intact IgG1 (PDB ID: 1IGY). Adapted from Harris et al. (1998). from publication: Ig Constant Region Effects on Variable Region Structure and ...

Download scientific diagram | | Crystal structure of intact IgG 1 (PDB ID: 1IGY). Adapted from Harris et al. (1998). ... (V L ) regions on constant human fragment (F C ) portion of IgG1 …

This model of human IgG1 was created by E. A. Padlin -- "Anatomy of the Antibody Molecule," Molecular Immunology 31:169 (1994) -- and the complete coordinates can be downloaded …