Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized neutral peptide believed to be …

IGF受体分两型，即IGF-Ⅰ受体（IGF-ⅠR）和IGF-Ⅱ受体（IGF-ⅡR），前者属酪氨酸激酶型受体，是由两个α亚基组成异源四聚体糖蛋白；后者没有氨酸激酶活性。 IGF是一类多功能细胞调 …

胰岛素样生长因子2 (insulin-like growth factor 2，Igf2)基因是最早发现的内源性印迹基因，其表达、调控不遵循 孟德尔遗传规律。 Igf2是一种多功能 细胞增殖 调控因子，在细胞的分化，增殖 …

2022年6月1日 · IGF-2是胚胎生长发育因子，是妊娠期主要的促生长激素。 它还参与细胞增殖、生长、迁移、分化和存活的调节。 此外，IGF-2在多种看似无关的癌症如乳腺癌、结肠癌和肺癌 …

The insulin-like growth factor (IGF) system regulates metabolic and mitogenic signaling through an intricate network of related receptors and hormones. IGF-II is one of several hormones …

2024年12月25日 · Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue …

Insulin-like growth factor II (IGF-II) plays a key role in mammalian growth, influencing foetal cell division and differentiation and possibly metabolic regulation. The mature 67 amino acid …

IGF-I has effects via the circulation and locally within tissues to regulate cellular growth, differentiation, and survival, thereby controlling overall body growth. IGF-II levels are highest …

2019年10月6日 · The IGF-II gene is adjacent to the insulin gene, which is a result of gene duplication, but has evolved to be considerably more complicated. It was one of the first genes …

Insulin-like growth factor two (IGF-II) is a key protein regulating growth, particularly during normal fetal development, but it is also often dysregulated during tumorigenesis [1, 2, 3]. In this …