2024年12月25日 · IGF2BP1 (Insulin Like Growth Factor 2 MRNA Binding Protein 1) is a Protein Coding gene. Diseases associated with IGF2BP1 include Spermatogenic Failure 19 and …

Insulin-like growth factor 2 mRNA-binding protein 1 is a protein that in humans is encoded by the IGF2BP1 gene. [5] [6] [7] This gene encodes a member of the IGF-II mRNA-binding protein …

2018年6月28日 · IGF2BP1 serves as a post-transcriptional fine-tuner regulating the expression of some essential mRNA targets required for the control of tumor cell proliferation and growth, …

2024年9月28日 · In this review, we provide a comprehensive overview of the discovery and molecular structure of IGF2BP1, along with recent studies on its role in regulating …

Within this review, we will provide an overview of IGF2BP1, including its tissue distribution, expression, molecular targets in the context of tumorigenesis and its inhibitors. Our main focus …

2024年10月20日 · By using proteomics, we demonstrate that phosphorylation of IGF2BP1 at S181 in a disordered linker is regulated in a stress-dependent manner. Phosphomimetic …

2025年2月9日 · IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer. TRIM71 binds to IMP1 and is capable of positive and negative regulation of …

2018年6月30日 · IGF2BP1作为转录后微调剂，可调节某些必需的mRNA靶标的表达，这些靶标是控制肿瘤细胞增殖和生长，侵袭和化学耐药性所需的，与各种类型的人类癌症的较差的总体生 …

该基因编码胰岛素样生长因子 2 mRNA 结合蛋白家族的成员。 该基因编码的蛋白质包含四个 K 同源结构域和两个 RNA 识别基序。 它通过结合某些基因的 mRNA 发挥作用，包括胰岛素样生 …

Insulin-like growth factor 2 mRNA-binding proteins (IGF2BP1, IGF2BP2, and IGF2BP3) are a family of RNA-binding proteins that play an essential role in the development and disease by …