Hedgehog family proteins are essential secreted signaling molecules that regulate a variety of developmental processes including growth, patterning and morphogenesis. The protein …

Recombinant Human Hedgehog Homolog, Indian (IHH) is a purified Prokaryotic Protein. Purity: >90% by SDS-PAGE. Host: E. coli. Endotoxin Level: 1.0EU per 1ug, by the LAL method. …

Enables patched binding activity. Involved in several processes, including heart looping; positive regulation of smoothened signaling pathway; and regulation of T cell differentiation. Acts …

2017年11月7日 · In the present study, Ihh knockdown was demonstrated to significantly inhibit cell growth and increase the apoptosis rate compared with NC cells. Downregulation of Ihh …

2020年12月1日 · Recombinant human/mouse IHH (cat#31705-HH/CF, R&D systems, MN, USA) was reconstituted in dH 2 O at 100 μg/mL and added to chondrocyte cultures to give a final …

Indian hedgehog protein (Ihh) is evolutionarily conserved and serves important roles in controlling the differentiation of progenitor cells into osteoblasts. Ihh null mutant mice exhibit a failure of …

Ihh plays an important role in bone development and maintains bone balance before and after birth. Activation of Ihh has been reported to promote chondrocyte hypertrophy in human …

Ihh induces chondrocyte hypertrophy and regulates type X collagen and MMPs in OA chondrocytes. Human OA chondrocytes were transfected with Ihh siRNA or treated with …

2024年12月25日 · IHH (Indian Hedgehog Signaling Molecule) is a Protein Coding gene. Diseases associated with IHH include Brachydactyly, Type A1 and Acrocapitofemoral Dysplasia. Among …

2020年7月3日 · Activation of Ihh has been reported to promote chondrocyte hypertrophy in human osteoarthritic cartilage and cultured chicken chondrocytes . Previous studies suggest …