The unit is named CSIR-IICB Translational Research Unit of Excellence (TRUE) whose overall mandate is to develop state-of-the-art fundamental innovation and further translate the indigenous innovations into affordable technology.

IICB-TRUE Facilities @ TRUE Incubation Centre Genomic Facility Animal House Faculty Cancer Biology & Inflammatory Disorder Cell Biology & Physiology Infectious Diseases & Immunology Molecular Genetics ...

Email: [email protected]. Designation: Chief Scientist (CSIR-IICB) and Professor, AcSIR

1 Cancer Biology and Inflammatory Disorder Division, Council of Scientific and Industrial Research-Indian Institute of Chemical Biology (CSIR-IICB), TRUE Campus, CN-6, Sector-V, Salt Lake, Kolkata- 700091 & 4, Raja S.C. Mullick Road, Jadavpur, Kolkata 700032, India.

We spotlight the diverse impact of E3 ligases and DUBs on CRC's biological processes and their remarkable versatility. We closely examine their specific influence on vital signaling pathways, particularly Wnt/β-catenin and NF-κB. Understanding these regulatory mechanisms is crucial for unravelling the complexities of CRC progression.

With applications to its identification as a prognostic biomarker, thus predicting response to advanced glioma therapy, this review aims to concentrate on the mechanistic role and regulation of MGMT gene expression at epigenetic, transcriptional, post-transcriptional, and post-translational levels functioning under the control of multiple signal...

2024年1月23日 · Drugs (agonist/inhibitors) enhance treatment efficacy depending on tumour subtypes. a Acute cGAS-STING signalling promotes anti-tumour immunity through activation of transcription factors like NF-κB and IRF3. b Chronic cGAS-STING signalling leads to immune evasion through ER stress response.

IICB-TRUE Facilities @ TRUE Incubation Centre Genomic Facility Animal House Faculty Cancer Biology & Inflammatory Disorder Cell Biology & Physiology Infectious Diseases & Immunology Molecular Genetics ...

‪Chief Scientist; Head - Cancer Biology; Ex-Scientist-In-Charge, CSIR-IICB(TRUE), Salt Lake Campus‬ - ‪‪Cited by 3,874‬‬ - ‪Signal Transduction in Cancer & Stem Cells‬ - ‪Targeted Drug Delivery...

CSIR-IICB is one of the major laboratories in India which initiated, right from its inception, multidisciplinary concerted efforts for conducting basic research on infectious diseases, specifically leishmaniasis and cholera, along with the development of technologies for the diagnosis, immunoprophylaxis, and chemotherapy of the diseases.