Transcription factors IIE and IIH and ATP hydrolysis direct …
1994年4月8日 · Using a defined RNA polymerase II (pol II) transcription system, we have investigated the roles of basal factors at discrete stages during the transcription cycle (e.g., …
Transcription Factors IIE and IIH and ATP Hydrolysis Direct Promoter Clearance by RNA Poiymeke II James A. Goodrich and Robert Tjian Howard Hughes Medical Institute …
Efficient production of recombinant human transcription factor IIE
2004年4月1日 · In this paper, we show that our recombinant human TFIIE is fully functional to stabilize a pre-initiation complex, consisting of promoter DNA, TBP, TFIIB, RNA polymerase II, …
Opening of an RNA polymerase II promoter occurs in two distinct …
1996年4月4日 · We have studied promoter opening in assays reconstituted with purified RNA polymerase II and basal transcription factors. We found that creating a region of heteroduplex …
We propose that IIH functions as a molecular wrench: rotating downstream DNA relative to Þxed upstream protein-DNA interactions, thereby generating torque on, and melting, the intervening …
Transcription factors IIE and IIH and ATP hydrolysis direct …
1994年4月8日 · Transcription factor IIE binds preferentially to RNA polymerase Ila and recruits TFIIH: a model for promoter clearance. Genes Dev. 8, 515-524. Recommended articles
Opening of an RNA polymerase II promoter occurs in two
1996年4月1日 · We have studied promoter opening in assays reconstituted with purified RNA polymerase II and basal transcription factors. We found that creating a region of heteroduplex …
Transcription factor IIH: A key player in the cellular response to …
1999年1月1日 · TFIIH (transcription factor IIH) is a multiprotein complex consisting of nine subunits initially characterized as a basal transcription factor required for initiation of protein …
Factors involved in specific transcription by mammalian RNA
1992年2月5日 · Two new factors required for transcription of class II genes have been identified. These factors, TFIIH and TFIIJ, were required together with the previously described general …
Mechanism of ATP-Dependent Promoter Melting by Transcription Factor IIH
2000年5月26日 · We propose that IIH functions as a molecular wrench: rotating downstream DNA relative to fixed upstream protein-DNA interactions, thereby generating torque on, and melting, …