Interleukin 35 (IL-35) is a recently discovered anti-inflammatory cytokine from the IL-12 family. Member of IL-12 family - IL-35 is produced by wide range of regulatory lymphocytes and plays …

IL-35 是 2002 年在第 13 届免疫学国际会议上被正式命名的一种新的抗炎 / 免疫抑制细胞因子 。 2007 年， Vignali 和 Liew 2 个小组分别发表了有关 IL-35 生物学功能的论文 ，使其成为近期免 …

白细胞介素35 (IL-35)是由调节性而不是效应性T细胞产生的细胞因子，是IL-12家族中的一员，在免疫抑制中起作用。 它是一个由IL-12α链和IL-27β链组成的二聚体蛋白，分别由两个独立的基 …

il-35. 与il-10、tgf-β和il-4相比，il-35是一种异二聚体且相对较新发现的细胞因子，属于il-12家族细胞因子，由p35和ebi3亚单位组成。il-35已被证明在良性和恶性肿瘤的发展中发挥重要作用，包 …

Interleukin-35 (IL-35), an inhibitory cytokine that belongs to the IL-12 family, is capable of potently suppressing T cell proliferation and inducing IL-35-producing induced regulatory T cells (iTr35) …

2019年1月25日 · Interleukin-35 (IL-35) is a recently identified heterodimeric cytokine in the IL-12 family. It consists of an IL-12 subunit α chain (P35) and IL-27 subunit Epstein–Barr virus …

Interleukin-35 (IL-35), an inhibitory cytokine that belongs to the IL-12 family, is capable of potently suppressing T cell proliferation and inducing IL-35-producing induced regulatory T cells (iTr35) …

2021年5月21日 · Interleukin-35 (IL-35) is a heterodimeric cytokine composed of Epstein-Barr virus-induced gene 3 (EBI3) and IL-12p35 that has recently been shown to play diverse and …

2017年9月28日 · Interleukin 35 (IL-35) is a heterodimeric cytokine composed of IL-12p35 and Ebi3 subunits. IL-35 suppresses autoimmune diseases while preventing host defense to …

IL-35 induces the expansion of a subset of regulatory T cells (Tregs) and Bregs and mediates their suppressive function and inhibits Th17 cells. It also upregulates osteoprotegerin and …