2017年9月1日 · 白细胞介素 20（il-20）是近来发现的白细胞介素 10 相关细胞因子家族的新成员；il-20 能够调节皮肤正常生理功能，活化角质细胞中的 stat3 途径，促进一些细胞因子、趋化因子的大量表达，从而调节皮肤早期炎症的发生。

The Ilyushin Il-20M (Russian: Ильюшин Ил-20М , NATO code name : "Coot-A" ) is a COMINT / ELINT surveillance - reconnaissance aircraft variant of the Ilyushin Il-18. It was first observed by NATO in 1978. The first flight took place on March 21, 1968, and the …

Interleukin 20 (IL20) is a protein that is in humans encoded by the IL20 gene which is located in close proximity to the IL-10 gene on the 1q32 chromosome. [5][6] IL-20 is a part of an IL-20 subfamily which is a part of a larger IL-10 family. [5] IL-20 subfamily also includes other cytokines, including IL-19, IL-20, IL-22, IL-24, and IL-26. [5] .

2014年11月25日 · IL-20 subfamily cytokines stimulate the proliferation of epithelial cells and also their production of antimicrobial proteins, and pro-inflammatory cytokines and chemokines. All of these...

2024年12月25日 · IL20 (Interleukin 20) is a Protein Coding gene. Diseases associated with IL20 include Psoriasis and Pelvic Organ Prolapse. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity and interleukin-20 receptor binding.

2010年10月1日 · IL-20 shares the highest amino-acid sequence identity with IL-10, IL-24 and IL-19. IL-20 is secreted by immune cells and activated epithelial cells like keratinocytes. A high expression of the corresponding IL-20 receptor chains is detected on epithelial cells.

IL-20R cytokines can be expressed by both immune cells and epithelial cells, and are important for their interaction. In general, these cytokines are considered to be associated with pathogenesis of chronic inflammation and autoimmune diseases, including psoriasis, rheumatoid arthritis and inflammatory bowel disease.

Members of the IL-20 subfamily facilitate the communication between leukocytes and epithelial cells, thereby enhancing innate defence mechanisms and tissue repair processes at epithelial surfaces. In this Review, we describe the cellular sources and targets of the IL-20 subfamily cytokines, and we detail how their expression is regulated.

IL-20 belongs to the IL-10 family and plays a role in skin inflammation and the development of hematopoietic cells. Little is known about its other biological functions and clinical implications, however. Updated information about IL-20, such as its …

The Ilyushin Il-20 was a Soviet prototype for a heavily armored ground-attack aircraft to replace the Ilyushin Il-10. It featured a number of innovative concepts including a cockpit mounted on top of the engine, directly behind the propeller , and wing-mounted autocannon that could be adjusted on the ground to fire level or depressed 23° to ...