Imipenem (trade name Primaxin among others) is a synthetic β-lactam antibiotic belonging to the carbapenems chemical class. developed by Merck scientists Burton Christensen, William Leanza, and Kenneth Wildonger in the mid-1970s. [1]

2023年9月7日 · What is imipenem and cilastatin? Imipenem and cilastatin is an antibiotic that is used in adults and children to treat bacterial infections of the heart, lungs, bladder, kidneys, skin, blood, bones, joints, stomach, or female reproductive organs. Imipenem and cilastatin may also be used for purposes not listed in this medication guide.

Imipenem is a carbapenem antibiotic normally administered with cilastatin to treat a variety of infections. Imipenem is a semisynthetic thienamycin that has a wide spectrum of antibacterial activity against gram-negative and gram-positive aerobic and anaerobic bacteria, including many multiresistant strains.

亚胺培南（INN：imipenem）是一种半合成的碳青霉烯类 抗生素， 属于β-内酰胺类。 亚胺培南主要抑制细菌细胞壁合成，抗菌活性极高，对革兰氏阴性菌、阳性菌、厌氧菌都有抗菌作用，也可用于耐多药结核菌 [ 1 ] 。

Medscape - Indication-specific dosing for Primaxin (imipenem/cilastatin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and...

2023年9月7日 · Detailed Cilastatin / Imipenem dosage information for adults and children. Includes dosages for Bacterial Infection, Urinary Tract Infection, Bronchitis and more; plus renal, liver and dialysis adjustments.

2024年11月1日 · Imipenem/cilastatin is an antibiotic that is commonly used to treat the following serious infections caused by certain bacteria. Lung infections, such as bronchitis or pneumonia

PRIMAXIN for intravenous use is a combination of imipenem, a penem antibacterial, and cilastatin, a renal dehydropeptidase inhibitor, indicated for the treatment of the following serious...

Imipenem is a beta-lactam antibiotic belongings to the subgroup of carbapenems. Imipenem is active against aerobic and anaerobic Gram positive as well as Gram negative bacteria including Pseudomonas aeruginosa and the Enterococcus. It exerts a …

Imipenem là một kháng sinh nhóm Beta - Lactam và có phổ kháng khuẩn rất rộng. Thuốc có cơ chế diệt khuẩn nhanh nhờ sự tương tác trên màng ngoài của vi khuẩn thông qua các protein gắn kết với Penicillin (PBP) trên đó.