Brain ischemia triggers inflammation as a response necrotic cells followed by the generation of reactive oxygen species (ROS), although many other factors have yet to be identified. Once …

Inflammation plays an important role in the pathogenesis of ischemic stroke and other forms of ischemic brain injury. Experimentally and clinically, the brain responds to ischemic injury with …

2023年7月3日 · Neuroinflammation is a crucial process following acute ischemic stroke (AIS) and hemorrhagic stroke (HS). In AIS, neuroinflammation is initiated within minutes of the ischemia …

2019年7月10日 · The proinflammatory signals from immune mediators rapidly activate resident cells and influence infiltration of a wide range of inflammatory cells (neutrophils, …

Research has shown that in the acute phase, neuroinflammatory cascades lead to apoptosis, disruption of the blood–brain barrier, cerebral edema, and hemorrhagic transformation, while …

5 天之前 · Background Inflammatory mechanisms play a significant role in ischemic stroke. Peripheral neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic …

2021年11月6日 · Overview of animal models for the study of neuroinflammation in the post-ischemic brain. Different therapeutic approaches and pharmacological candidates for the …

2019年7月8日 · Stroke, including acute ischaemic stroke and intracerebral haemorrhage, results in neuronal cell death and the release of factors such as damage-associated molecular …

2018年6月30日 · Neuroinflammation after ischemic stroke may destroy, or protect and repair brain tissues [1]. Inflammatory response after ischemic stroke involves the activation of brain …

2023年9月1日 · In the field of inflammation research in cerebral ischemia-reperfusion injury, the terms "Blood-brain barrier," "Oxidative stress," "Neural regeneration," "Toll-like receptor-4," …