Multiple Myeloma–VTD (IV-28)-Bortezomib (IV)-Dexamethasone-Thalidomide (28 day) - metoclopramide 10mg three times a day oral when required Thromboprophylaxis according to …

It is a treatment for people with myeloma who are able to have an autologous stem cell transplant . How does DVTD work? Daratumumab is a type of targeted cancer drug called a monoclonal …

2015年9月6日 · In this study, the improved VTD regimen by changing bortezomib from intravenous administration to subcutaneous injection showed noninferior efficacy to standard …

How does VTd work? Each of the medications in VTd is designed to kill or slow the growth of myeloma cells. V - Velcade® (Bortezomib) T - Thalidomide (Thalomid®) d - dexamethasone …

2025年2月18日 · A recent meta-analysis evaluated the efficacy and safety of two induction regimens: bortezomib, thalidomide, and dexamethasone (VTD) and bortezomib, lenalidomide, …

Consolidation: 2 cycles of D-VTD as consolidation therapy post-ASCT. This regimen was based on CASSIOPEIA trial and has been slightly modified to simplify the schedule (e.g., SC instead …

2025年1月28日 · DARZALEX ® (daratumumab) injection, for intravenous use Initial U.S. Approval: 2015 INDICATIONS AND USAGE DARZALEX is a CD38-directed cytolytic antibody …

2020年5月25日 · Background: In the phase 3 CASSIOPEIA study, D-VTd significantly improved outcomes vs VTd in TE NDMM pts at an 18.8-mo median follow-up. To allow earlier diagnosis …

6 天之前 · D-VTd followed by daratumumab maintenance consistently produced the highest landmark, accumulative, and sustained MRD-negativity rates (10-5 and 10-6), translating to …

The multi-agent chemotherapy regimen VDT-PACE (bortezomib, high dose dexamethasone, thalidomide, cisplatin, doxorubicin (adriamycin), cyclophosphamide and etoposide) has been …