Engineered CRO-CD7 CAR-NK cells derived from pluripotent stem …
2025年1月26日 · Results: The CD7 KO-CD7 CAR-iNK cells derived from CD7 KO-CD7 CAR-hPSCs effectively avoided fratricide, demonstrated normal expansion, and exhibited potent …
CD7 protein plays a crucial role in T cell infiltration in tumors
CD7, also known as GP40, is a membrane-expressed protein that belongs to the immunoglobulin superfamily. CD7 expression was detected in T cells and subsequently shown to also be …
【研究报告】CD7靶点：清君侧 - 健康界
2022年8月22日 · CD7通常表达于85%的外周血T细胞和NK细胞及其前体细胞，是一种辅助T细胞活化和与其他免疫亚群细胞相互作用的共刺激受体蛋白。 某些正常T细胞的CD7不表达，其对T …
Structure and function of the CD7 molecule - PubMed
CD7 is a single-domain Ig superfamily molecule expressed on human T and NK cells, as well as on cells in the early stages of T, B, and myeloid cell differentiation. CD7 is highly expressed on …
医疗观察丨另辟蹊径，CD7靶点CAR-T拓展血液瘤新适应症 - 知乎
2023年11月3日 · cd7靶点car-t疗法脱颖而出， 挑战与机遇并存. 聚焦新靶点，cd7靶向car-t疗法优势显著. cd7是一种单链跨膜糖蛋白，表达在t细胞和nk细胞及其前体细胞膜表面。在淋巴细胞 …
CD7 分子是一种相对分子质量为40×103的细胞表面糖蛋白,属于免疫球蛋白超家族成员,在淋巴细胞发育成熟过程中发挥重要作用。 当CD7分子黏附抗体或抗体衍生物后可快速发生内吞作用,这 …
CD7 Gene - GeneCards | CD7 Protein | CD7 Antibody
2024年12月24日 · CD7 (CD7 Molecule) is a Protein Coding gene. Diseases associated with CD7 include Mycosis Fungoides and Lymphoblastic Lymphoma. Among its related pathways is …
陆道培医学团队在Blood杂志发表CD7 CAR-T治疗急性髓系白血病 …
2025年1月14日 · 在该研究中，陆佩华院长带领团队创新性地采用基于纳米抗体的CD7 CAR-T治疗急性髓系白血病，研究结果不仅在肿瘤杀伤力和安全性上取得了显著进展，更为难治复发急性 …
Phenotypic and transcriptomic profiling of induced pluripotent …
2024年11月13日 · Within the iNK cluster, we observed a gradual increase in the expressions of CD7, CD94, and CD16, ranging from low to high levels. Moreover, iNK cells exhibited low …
CD7 targeted "off-the-shelf" CAR-T demonstrates robust in vivo
GC027 is an "off-the-shelf" allogeneic CD7 targeted CAR-T therapeutic product for T cell malignancies. It demonstrated superior cell expansion and antileukemia efficacy in mouse …