
视网膜及视路解剖示意图 - 知乎 - 知乎专栏
神经节细胞层(ganglion cell layer,GCL) - 神经节细胞的细胞体组成,还有 Müller 细胞、神经胶质细胞、及视网膜血管的分支 - 大多数区域为1层,颞侧为2层,黄斑区8-10层。
Importance of Müller Cells - PMC - PubMed Central (PMC)
The uppermost portion of the MCs creates the internal limiting membrane, which separates the retina from the vitreous. The cell bodies sit on the inner nuclear layer. The apical portion extends to the rear to form the outer limiting membrane and separates the internal and external parts of the photoreceptors.
Role of growth factors and internal limiting membrane …
2021年1月1日 · In summary, this study revealed the combinatorial effects of various growth factors and individual internal limiting membrane constituents. This may assist Müller cell migration together with the macular hole healing process.
The internal limiting membrane: roles in retinal development …
The internal limiting membrane (ILM) is the basement membrane at the ocular vitreoretinal interface. While the ILM is essential for normal retinal development, it is dispensable in adulthood. Moreover, the ILM may constitute a significant barrier to emerging ocular therapeutics, such as viral gene therapy or stem cell transplantation.
In vitro culture Muller cell model to study the role of inverted ...
2021年3月8日 · Inverted internal limiting membrane (ILM) flap may constitute a scaffold for Muller cells whose migration and proliferation on its surface begin the process of macular hole closure. The goal of the study was to establish an in vitro model of …
Internal limiting membrane: The innermost retinal barrier
2017年1月1日 · The internal limiting membrane (ILM) is the basement membrane of the retinal Müller cells at the vitreoretinal interface. It contains various high molecular weight extracellular matrix proteins like collagen (type IV, XVIII), laminin, fibronectin, nidogen 1 and 2, agrin, and perlecan [1], [2].
Transdifferentiation effects and related mechanisms of nerve …
2019年3月1日 · In this study, we investigated the pro-proliferative, pro-transdifferentiation effects and mechanisms of nerve growth factor (NGF), internal limiting membrane (ILM), and NGF+ILM on Müller cells.
Inverted internal limiting membrane (ILM) flap may constitute a scaffold for Muller cells whose migration and proliferation on its surface begin the process of macular hole closure. The goal of the study was to establish an in vitro model of the interaction between ILM and the Muller cells. Vitrectomy with inverted ILM flap was performed in 23
Role of growth factors and internal limiting membrane
This study investigated the effects of growth factors and internal limiting membrane components on Müller cell migration. We studied the effects of epidermal growth factor (EGF), fibroblast growth factor (FGF), somatomedin (IGF-1), platelet derived growth factor (PDGF), and stromal cell-derived fact …
The relationship between a dissociated optic nerve fibre layer ...
Purpose: A dissociated optic nerve fibre layer (DONFL) is a characteristic change noted in inner retinal morphology after internal limiting membrane (ILM) peeling. It is thought to be due to trauma to Muller cells as the ILM is peeled from their attached end plates.
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