Pericentric inversion 9 is a common chromosome variant with an incidence of approximately 1.6% in the general population [1]. Despite the relatively high incidence of this finding, there is debate in the literature over its clinical significance resulting in confusion about how to counsel patients regarding the medical management of this variant.

Chromosome 9 is highly susceptible to structural rearrangements, specifically to pericentric inversions. Various investigators have posited that inv(9) with different breakpoints could be the cause of several abnormal conditions in individuals, whereas others have considered it …

One of the most common and benign variants of normal human karyotype is pericentric inversion of chromosome 9 (inv[9][p11q13]). Despite being categorized as a normal variant, there are several reports of its association with various disease conditions.

2005年7月1日 · Pericentric inversion of the heterochromatic region of chromosome 9 [inv (9)] is a common heteromorphism in the general population. It is presumed familial as there are no reports of de novo inv (9) chromosomes in constitutional karyotypes.

2024年10月2日 · Pericentric inversion of chromosome 9, referred to as inv (9), is a frequent finding in human karyotype, ranging from 1% to 4% in the general population. Among the countless possibilities of pericentric inversions of chromosome 9, the inv (9) (p12q13) variant is the most common.

Pericentric inversion of the chromosome 9, inv (9) (p11q13), is such a common occurrence that some cytogeneticists would consider them as normal variants. The incidence is said to be about 1% to 1.65% in the general population.

2005年7月1日 · Pericentric inversion of the heterochromatic region of chromosome 9 [inv (9)] is a common heteromorphism in the general population. It is presumed familial as there are no reports of de novo inv (9) chromosomes in constitutional karyotypes.

One of the frequent occurrences in chromosome rearrangements is pericentric inversion of the Chromosome 9; inv (9) (p11q12), which is consider to be the variant of normal karyotype.

Pericentric inversion 9 is a common chromosome variant with an incidence of approximately 1.6% in the general population [1]. Despite the relatively high incidence of this finding, there is debate in the literature over its clinical significance resulting in confusion about how to counsel patients regarding the med-ical management of this variant.

2019年11月16日 · Fifty-two trophectoderm biopsy samples from seven couples were sent to a single lab for PGT-SR for an inversion 9 variant with concurrent 24 chromosome PGT-A using single-nucleotide polymorphism (SNP) microarrays with bioinformatics.