Intraoperative electron radiation therapy is the application of electron radiation directly to the residual tumor or tumor bed during cancer surgery. [1][2] Electron beams are useful for intraoperative radiation treatment because, depending on the electron energy, the dose falls off rapidly behind the target site, therefore sparing underlying he...

Intraoperative radiation therapy (IORT) constitutes delivery of radiation to the tumour/tumour bed while the area is exposed during surgery. IORT is capable of delivering high doses of radiation, precisely to the tumour bed with minimal exposure to the surrounding healthy tissues.

Four decades ago, intraoperative electron radiation therapy (IOeRT) was developed to improve precision in local cancer treatment by combining real-time surgical exploration and resection with high-energy electron irradiation.

2022年7月29日 · IOeRT represents an evidence-based approach for several tumor types. A specific risk analysis for local recurrences supports the identification of cancer models that are candidates for FLASH studies.

Intra-operative electron radiotherapy (IOERT) directly delivers a large fraction of radiation to at-risk margins during surgery. However, the precise benefit of IOERT in patients with locally advanced and locally recurrent colorectal cancer (LACC/LRCC) is unclear.

2023年11月10日 · Intraoperative radiation therapy (IORT) is a radiation technique applying a single fraction with a high dose during surgery. We report the first abdomino-pelvic application of an image-guided intraoperative electron radiation therapy with intraoperative real time dose calculation based on the individual intraoperative patient anatomy.

2024年5月1日 · Among the different cancer treatment modalities available today, Intra Operative Radiation Therapy, delivered with electrons (IOeRT), can be used to effectively deliver the prescribed dose to the target volume maximising the local treatment efficacy decreasing the risk of local cancer recurrence [1], [2], [3], [4], [5], [6], [7].

IOERT (intraoperative electron radiotherapy) in breast cancer is used either as a boost (10-12 Gy) followed by whole breast irradiation (WBI) or as full-dose partial breast irradiation (PBI, 20-24 Gy) during breast-conserving surgery. IOERT has the longest evidence of all IORT techniques.

Intra-operative radiation therapy (IORT) is a high-dose, single-session partial breast irradiation technique performed during breast-conserving surgery, and it is indicated either as an exclusive treatment in a subgroup of patients considered at low risk for LR [7] or as an anticipated boost to the tumor bed followed by WBI [8, 9].

2014年4月14日 · IOERT is a way of administering radiotherapy at low cost, reducing the risk of a complete lack of irradiation. It is applied directly to the tumor bed using visual guidance, eliminating the possibility of a geometric miss of the tumor bed, which may still be possible with EBRT despite improved radiotherapy imaging approaches.