Ionophores are chemical compounds that reversibly bind and transport ions through biological membranes in the absence of a protein pore. This can disrupt the membrane potential, and thus these substances could exhibit cytotoxic properties. [1] .

An ionophore is a small, lipid-soluble molecule that acts as an ion carrier, facilitating the transport of ions across membranes down their electrochemical gradient. They can be classified as channel formers or mobile carriers based on their mechanism of action. You might find these chapters and articles relevant to this topic.

Un ionóforo es una molécula soluble en lípidos, usualmente sintetizada por microorganismos para transportar iones a través de una bicapa lipídica de membrana celular. Existen dos clasificaciones para los ionóforos.

Calcium ionophores are generally assumed to directly facilitate the transport of Ca2+ across the plasma membrane. The ability of Ca2+ ionophores ionomycin and A23187 to increase Ca2+ concentration in the cytosol ( [Ca2+]i) in different cells was analyzed in …

Calcium chelators which exhibit changes in their optical properties can be used as buffers and indicators of free [Ca 2+] and those which are hydrophobic in nature can be used as Ca ionophores to alter (or control) free [Ca 2+] inside cells, organelles, or vesicles.

Ionophores are key components in ISEs that determine the selectivity and sensitivity of the electrode toward the target ion. The purpose of this review is to provide insights into selecting effective ionophores for potentiometric applications in detecting Pb 2+ contamination in …

2023年1月15日 · For many years, ionophores have been used to control coccidiosis in poultry. However, misuse of ionophores can cause toxicity with significant clinical symptoms. The most critical factors influencing ionophores' toxicity are administration dose, species, and animal age.

Ionofor ("pembawa ion") adalah senyawa kimia yang dapat mengikat ion secara reversibel (bolak-balik: artinya ion yang telah diikat itu bisa dilepas kembali). Dalam tubuh makhluk hidup, banyak ionofor larut dalam lemak, sehingga berfungsi membawa …

2021年7月15日 · Calcium ionophore (A23187) is a highly selective calcium ionophore, which can form stable complex with Ca 2+ and pass through the cell membrane at will, effectively increasing intracellular Ca 2+ levels. It has been reported that calcium ionophore (A23187) can activate oocytes and obtain normal embryos.

En química, un ionóforo (del griego ion y -phore 'portador de iones') es una especie química que une reversiblemente los iones. Muchos ionóforos son entidades liposolubles que transportan iones a través de la membrana celular.