IPSET-thrombosis model provides objective estimates of the probability of thrombotic events in patients with newly diagnosed ET. Answer all 4 Questions given below:- 1. Patient age is. 2. Prior thrombotic event in patient. 3. Cardiovascular risk factors present (One or more of: hypertension, diabetes mellitus, active smoking) 4.

2022年1月13日 · International Prognostic Score of thrombosis in World Health Organization – essential thrombocythemia (IPSET-thrombosis). IPSET-thrombosis model provides objective estimates of the probability of thrombotic events in patients with newly diagnosed ET.

The thrombotic risk score named IPSET-t takes into account the cardiovascular risk factors (CVR) and stratifies patients into low-, intermediate-, and high-risk group . Recently, a revision of IPSET-thrombosis was achieved by the re-analysis of the original IPSET-thrombosis data set.

A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment. Blood. 2012; 120 (6):1197-1201.

2018年1月10日 · Current drug therapy for myeloproliferative neoplasms, including essential thrombocythemia (ET) and polycythemia vera (PV), is neither curative nor has it been shown to prolong survival....

In this study of 585 patients with ET (median age 68 years; 61% female), we validated the revised IPSET-thrombosis by confirming significant differences in thrombosis risk between "very low" and "low" (HR 2.4, 95% CI 1.1 - 5.3) and between "intermediate" and "high" (HR 2.3, 95% CI 1.1 - …

2012年12月20日 · The present study presents a new prognostic model for thrombosis in ET, IPSET-thrombosis, that was developed to improve risk classification to optimize clinical decision making in individual patients. This model has several potential advantages over the previous conventional system, which was based on age and previous thrombosis and had ...

2024年6月25日 · Essential thrombocythemia (ET) is a chronic myeloproliferative neoplasm (MPN) that originates from a hematopoietic stem cell harboring a mutated JAK2, CALR, or MPL gene, or...

2015年11月27日 · Current risk stratification for thrombosis in essential thrombocythemia (ET) is two-tiered and considers low- and high-risk categories based on the respective absence or presence of either age >60 years or history of thrombosis. 1 In the recent International Prognostic Score for Thrombosis in ET (IPSET-thrombosis), age and history of thrombosis ...

2025年3月12日 · IPSET-thrombosis risk category for ET was low for 122 patients (45%), intermediate for 110 patients (41%) and high for 37 patients (14%). Patient characteristics are summarized in Table ...